alpha-GLUCOSIDASE AND alpha -AMYLASE INHIBITORY ACTIVITIES OF RAPHANUS SATIVUS LINN

Herbal medicine has been used for many years by different cultures around the world for the treatment of diabetes. There has been an enormous interest in the development of alternative medicines for type 2 diabetes, specifically screening for phytochemicals with the ability to delay or prevent glucose absorption. The goal of the present study is to evaluate the invitro antidiabetic activity of Raphanus sativus ethanolic extract and fractions by alpha-glucosidase and alpha -amylase inhibitory activity. Raphanus sativus ethanolic extract and fractions showed dose dependent inhibition of alpha- glucosidase and alpha -amylase enzyme and exhibited lower inhibitory activity than acarbose. The study revealed the antidiabetic potential and could be helpful to develop medicinal preparations and nutraceuticals and function foods for diabetes.