Evidence of Lifestyle Modification in the Management of Hypercholesterolemia

被引:95
|
作者
Mannu, G. S. [1 ]
Zaman, M. J. S. [2 ,3 ]
Gupta, A. [4 ]
Rehman, H. U. [5 ]
Myint, P. K. [1 ,6 ]
机构
[1] Norfolk & Norwich Univ Hosp, Norwich, Norfolk, England
[2] James Paget Univ Hosp, Great Yarmouth, Norfolk, England
[3] George Inst Global Hlth, Sydney, NSW, Australia
[4] West Wales Hosp, Dept Med, Carmarthen, Wales
[5] Regina Qu Appelle Hlth Reg, Regina, SK, Canada
[6] Univ East Anglia, Norwich Med Sch, Norwich Res Pk Cardiovasc Grp, Norwich, Norfolk, England
关键词
Coronary heart disease (CHD); hypercholesterolemia; CVD risk; lifestyle modification;
D O I
10.2174/1573403X11309010002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Coronary heart disease (CHD) is the leading cause of morbidity and mortality worldwide. The growth of ageing populations in developing countries with progressively urbanized lifestyles are major contributors. The key risk factors for CHD such as hypercholesterolemia, diabetes mellitus, and obesity are likely to increase in the future. These risk factors are modifiable through lifestyle. Objectives: To review current literature on the potential benefit of cholesterol lowering in CHD risk reduction with a particular focus on the evidence of non-pharmacological/lifestyle management of hypercholesterolemia. Methods: Medline/PubMed systematic search was conducted using a two-tier approach limited to all recent English language papers. Primary search was conducted using key words and phrases and all abstracts were subsequently screened and relevant papers were selected. The next tier of searching was conducted by (1) reviewing the citation lists of the selected papers and (2) by using PubMed weblink for related papers. Over 3600 reports were reviewed. Results: Target cholesterol levels set out in various guidelines could be achieved by lifestyle changes, including diet, weight reduction, and increased physical activity with the goal of reducing total cholesterol to <200 mg/dL and LDL-C <100mg/dL. Various dietary constituents such as green tea, plant sterols, soy protein have important influences on total cholesterol. Medical intervention should be reserved for those patients who have not reached this goal after 3 months of non-pharmacological approach. Conclusion: CHD remains as a leading cause of death worldwide and hypercholesterolemia is an important cause of CHD. Non-pharmacological methods provide initial as well as long-term measures to address this issue.
引用
收藏
页码:2 / 14
页数:13
相关论文
共 50 条
  • [1] Internet interventions to support lifestyle modification for diabetes management: A systematic review of the evidence
    Cotter, Alexander P.
    Durant, Nefertiti
    Agne, April A.
    Cherrington, Andrea L.
    JOURNAL OF DIABETES AND ITS COMPLICATIONS, 2014, 28 (02) : 243 - 251
  • [2] Lifestyle modification in the management of obesity: achievements and challenges
    Riccardo Dalle Grave
    Simona Calugi
    Marwan El Ghoch
    Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity, 2013, 18 : 339 - 349
  • [3] Lifestyle modification in the management of obesity: achievements and challenges
    Dalle Grave, Riccardo
    Calugi, Simona
    El Ghoch, Marwan
    EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY, 2013, 18 (04) : 339 - 349
  • [4] Role of lifestyle modification in the management of polycystic ovary syndrome
    Hoeger, Kathleen M.
    BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2006, 20 (02) : 293 - 310
  • [5] Lifestyle modification in the management of the metabolic syndrome: achievements and challenges
    Dalle Grave, Riccardo
    Calugi, Simona
    Centis, Elena
    Marzocchi, Rebecca
    El Ghoch, Marwan
    Marchesini, Giulio
    DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY, 2010, 3 : 373 - 385
  • [6] Management of the Metabolic Syndrome and Type 2 Diabetes Through Lifestyle Modification
    Magkos, Faidon
    Yannakoulia, Mary
    Chan, Jean L.
    Mantzoros, Christos S.
    ANNUAL REVIEW OF NUTRITION, 2009, 29 : 223 - 256
  • [7] The challenge of diet, exercise and lifestyle modification in the management of the obese diabetic patient
    JP Foreyt
    WS Carlos Poston
    International Journal of Obesity, 1999, 23 : S5 - S11
  • [8] The challenge of diet, exercise and lifestyle modification in the management of the obese diabetic patient
    Foreyt, JP
    Poston, WC
    INTERNATIONAL JOURNAL OF OBESITY, 1999, 23 (Suppl 7) : S5 - S11
  • [9] Culturally Tailored Lifestyle Modification Strategies for Hypertension Management: A Narrative Review
    Miezah, Dennis
    Hayman, Laura L.
    AMERICAN JOURNAL OF LIFESTYLE MEDICINE, 2024,
  • [10] Lifestyle Modification in Rheumatoid Arthritis: Dietary and Physical Activity Recommendations Based on Evidence
    Chehade, Leila
    Jaafar, Zeinab Amanda
    El Masri, Dana
    Zmerly, Hassan
    Kreidieh, Dima
    Tannir, Hana
    Itani, Leila
    El Ghoch, Marwan
    CURRENT RHEUMATOLOGY REVIEWS, 2019, 15 (03) : 209 - 214