APPROACHES TO STUDYING CELL-ADHESION MOLECULES IN ANGIOGENESIS

被引：98

作者：

BISCHOFF, J ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,DEPT SURG,BOSTON,MA 02115

来源：

TRENDS IN CELL BIOLOGY | 1995年 / 5卷 / 02期

关键词：

D O I：

10.1016/S0962-8924(00)88949-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Capillaries provide a vast interface between the blood and the tissues that is crucial for regulating nutrient delivery, blood coagulation and transmigration of leukocytes to sites of infection. The growth of new capillaries from pre-existing vessels (angiogenesis) is essential for normal embryogenesis and growth, but also occurs in the development of many diseases. Although relatively little is known about endothelial cell biology, progress is nevertheless being made towards understanding angiogenesis, and several laboratories have begun to identify, cell adhesion molecules that may be required for the growth of microvessels.

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页码：69 / 74

页数：6

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