Oncolytic viral therapy for pancreatic cancer: current research and future directions

被引：15
|
作者：
Ady, Justin W. [1 ]
Heffner, Jacqueline [1 ]
Klein, Elizabeth [1 ]
Fong, Yuman [1 ]
机构：
[1] Mem Sloan Kettering Canc Ctr, Dept Surg, New York, NY 10021 USA
来源：
ONCOLYTIC VIROTHERAPY | 2014年 / 3卷
关键词：
pancreatic cancer; oncolytic virus; review;
D O I：
10.2147/OV.S53858
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The development of targeted agents and chemotherapies for pancreatic cancer has only modestly affected clinical outcome and not changed 5-year survival. Fortunately the genetic and molecular mechanisms underlying pancreatic cancer are being rapidly uncovered and are providing opportunities for novel targeted therapies. Oncolytic viral therapy is one of the most promising targeted agents for pancreatic cancer. This review will look at the current state of the development of these self-replicating nanoparticles in the treatment of pancreatic cancer.
引用
收藏
页码：35 / 46
页数：12
相关论文
共 50 条
  • [41] Current status on the place of FOLFIRINOX in metastatic pancreatic cancer and future directions
    Lambert, Aurelien
    Gavoille, Celine
    Conroy, Thierry
    THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 2017, 10 (08) : 631 - 645
  • [42] HER family inhibitors in pancreatic cancer: current status and future directions
    Berz, David
    Miner, Thomas
    McCormack, Elise
    Safran, Howard
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2007, 11 (03) : 337 - 347
  • [43] Irreversible electroporation for the management of pancreatic cancer: Current data and future directions
    Spiliopoulos, Stavros
    Reppas, Lazaros
    Filippiadis, Dimitrios
    Delvecchio, Antonella
    Conticchio, Maria
    Memeo, Riccardo
    Inchingolo, Riccardo
    WORLD JOURNAL OF GASTROENTEROLOGY, 2023, 29 (02) : 223 - 231
  • [44] Irreversible electroporation for the management of pancreatic cancer:Current data and future directions
    Stavros Spiliopoulos
    Lazaros Reppas
    Dimitrios Filippiadis
    Antonella Delvecchio
    Maria Conticchio
    Riccardo Memeo
    Riccardo Inchingolo
    World Journal of Gastroenterology, 2023, 29 (02) : 223 - 231
  • [45] Adjuvant therapy in colon cancer: current status and future directions cancer
    Chau, I
    Cunningham, D
    CANCER TREATMENT REVIEWS, 2002, 28 (05) : 223 - 236
  • [46] Cell carriers for oncolytic viruses: current challenges and future directions
    Roy, Dominic G.
    Bell, John C.
    ONCOLYTIC VIROTHERAPY, 2013, 2 : 47 - 56
  • [47] Inhibiting CDK in Cancer Therapy: Current Evidence and Future Directions
    Vijayaraghavan, Smruthi
    Moulder, Stacy
    Keyomarsi, Khandan
    Layman, Rachel M.
    TARGETED ONCOLOGY, 2018, 13 (01) : 21 - 38
  • [48] Neoadjuvant therapy for gastric cancer: current evidence and future directions
    Newton, Andrew D.
    Datta, Jashodeep
    Loaiza-Bonilla, Arturo
    Karakousis, Giorgos C.
    Roses, Robert E.
    JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2015, 6 (05) : 534 - 543
  • [49] Current standards and future directions for prostate cancer radiation therapy
    Pinkawa, Michael
    Schoth, Felix
    Boehmer, Dirk
    Hatiboglu, Gencay
    Sharabi, Andrew
    Song, Danny
    Eble, Michael J.
    EXPERT REVIEW OF ANTICANCER THERAPY, 2013, 13 (01) : 75 - 88
  • [50] Adjuvant therapy of colon cancer: Current status and future directions
    Chung, Ki Young
    Saltz, Leonard B.
    CANCER JOURNAL, 2007, 13 (03): : 192 - 197
12345