EFFECT OF LOW PROTEIN-DIET ON MANGANESE NEUROTOXICITY .3. BRAIN NEUROTRANSMITTER LEVELS

被引：0
|
作者：
ALI, MM
MURTHY, RC
MANDAL, SK
CHANDRA, SV
机构：
[1] IND TOXICOL RES CTR, MET TOXIC, POB 80, LUCKNOW 226001, UTTAR PRADESH, INDIA
[2] CENT DRUG RES INST, DIV BIOMETRY & STAT, LUCKNOW 226001, UTTAR PRADESH, INDIA
来源：
NEUROBEHAVIORAL TOXICOLOGY AND TERATOLOGY | 1985年 / 7卷 / 05期
关键词：
D O I：
暂无
中图分类号：
R99 [毒物学（毒理学）];
学科分类号：
100405 ;
摘要：
The effect of concurrent low protein (10% casein) diet and manganese (Mn) exposure (3 mg/ml drinking water) on brain levels of dopamine (DA), norepinephrine (NE) and 5-hydroxytryptamine (5-HT) were investigated in Fo-growing (90 days exposure), Fo-diet rehabilitated (low .fwdarw. normal protein diet-28 days) and FI-weaned rats. Mn exposure in either diet group resulted in a significant increase in the DA and NE levels but a decrease in the 5-HT level. These effects were more pronounced in the rats fed the low protein diet, especially in the F1-offsprings. Diet rehabilitation reduced the effects of Mn exposure.
引用
收藏
页码：427 / 431
页数：5
相关论文
共 50 条
  • [1] EFFECT OF LOW PROTEIN-DIET ON MANGANESE NEUROTOXICITY .2. BRAIN GABA AND SEIZURE SUSCEPTIBILITY
    ALI, MM
    MURTHY, RC
    SAXENA, DK
    CHANDRA, SV
    NEUROBEHAVIORAL TOXICOLOGY AND TERATOLOGY, 1983, 5 (03): : 385 - 389
  • [2] EFFECT OF LOW PROTEIN-DIET ON MANGANESE NEUROTOXICITY .1. DEVELOPMENTAL AND BIOCHEMICAL-CHANGES
    ALI, MM
    MURTHY, RC
    SAXENA, DK
    SRIVASTAVA, RS
    CHANDRA, SV
    NEUROBEHAVIORAL TOXICOLOGY AND TERATOLOGY, 1983, 5 (03): : 377 - 383
  • [3] LOW PROTEIN-DIET MODIFIES ACRYLAMIDE NEUROTOXICITY
    KHANNA, VK
    HUSAIN, R
    SETH, PK
    TOXICOLOGY, 1988, 49 (2-3) : 395 - 401
  • [4] RENAL RESERVE IN DISEASE - EFFECT OF LOW PROTEIN-DIET
    BOSCH, JP
    GLABMAN, S
    LAUER, A
    CLINICAL RESEARCH, 1984, 32 (02): : A531 - A531
  • [5] LOW PROTEIN-DIET PREVENTS AND HIGH PROTEIN-DIET EXACERBATES ADRIAMYCIN GLOMERULOPATHY
    REMUZZI, G
    ZOJA, C
    REMUZZI, A
    ROSSINI, M
    BATTAGLIA, C
    BERTANI, T
    CLINICAL RESEARCH, 1985, 33 (02): : A496 - A496
  • [6] LOW PROTEIN-DIET PREVENTS AND HIGH PROTEIN-DIET EXACERBATES EXPERIMENTAL NEPHROSIS
    REMUZZI, G
    ZOJA, C
    REMUZZI, A
    ROSSINI, N
    BATTAGLIA, C
    BERTENI, T
    KIDNEY INTERNATIONAL, 1985, 27 (01) : 352 - 352
  • [7] LOW PROTEIN-DIET PREVENTS AND HIGH PROTEIN-DIET EXACERBATES ADRIAMYCIN (ADR) GLOMERULOPATHY
    REMUZZI, G
    ZOJA, C
    REMUZZI, A
    ROSSINI, M
    BATTAGLIA, C
    BERTANI, T
    KIDNEY INTERNATIONAL, 1985, 28 (02) : 274 - 274
  • [8] EFFECTS OF A LOW PROTEIN-DIET DURING PREGNANCY OF THE RHESUS-MONKEY .3. GROWTH OF INFANTS
    KOHRS, MB
    KERR, GR
    HARPER, AE
    AMERICAN JOURNAL OF CLINICAL NUTRITION, 1980, 33 (03) : 625 - 630
  • [9] EFFECT OF AMINO-ACID SUPPLEMENTATION TO LOW PROTEIN-DIET ON BRAIN AND PLASMA-LEVELS OF TRYPTOPHAN AND BRAIN 5-HYDROXYINDOLES IN RATS
    YOKOGOSHI, H
    IWATA, T
    ISHIDA, K
    YOSHIDA, A
    JOURNAL OF NUTRITION, 1987, 117 (01) : 42 - 47
  • [10] EFFECT OF LOW PROTEIN-DIET ON INTESTINAL TRANSPORT OF AMINO NITROGEN
    CHEESEMAN, CI
    DEVLIN, D
    CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1985, 63 (04) : AR7 - AR7
12345