CLONING AND SEQUENCING OF A NOVEL HEMOLYSIS GENE OF VIBRIO-CHOLERAE

被引：0

作者：

NAGAMUNE, K

YAMAMOTO, K

HONDA, T

机构：

来源：

FEMS MICROBIOLOGY LETTERS | 1995年 / 128卷 / 03期

关键词：

VIBRIO CHOLERAE; HEMOLYSIN; CYTOLYSIN;

D O I：

10.1111/j.1574-6968.1995.tb07534.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A hemolysis gene (hlx) which lyses sheep erythrocytes on blood agar plates when expressed in Escherichia coli was cloned from Vibrio cholerae. The cloned gene is predicted to encode a polypeptide of 92 amino acid residues with a deduced molecular mass of 10451. E. coli transformed with this gene lysed sheep, goose, horse and chicken erythrocytes but not those of guinea pig and human. The hlx gene was observed in classical- and El Tor-biotype V. cholerae 01, V. cholerae non-01, and V. mimicus, but not in V. parahaemolyticus.

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页码：265 / 269

页数：5

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