STEREOSPECIFIC SYNTHESIS OF (+)-MURICATACIN - A BIOLOGICALLY-ACTIVE ACETOGENIN DERIVATIVE

被引：70

作者：

FIGADERE, B

HARMANGE, JC

LAURENS, A

CAVE, A

机构：

[1] Laboratoire de Pharmacognosie, associé au C.N.R.S. Faculté de Pharmacie

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 51期

关键词：

ACETOGENINS; MURICATACIN; SYNTHESIS; BIOASSAYS; ANNONA MURICATA;

D O I：

10.1016/0040-4039(91)80528-E

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(+)-muricatacin and analogs have been synthesized without ambiguity about the absolute configuration at the C-4 and C-5 centres. The observed [alpha]D are reported as well as the results obtained for the cytotoxicity assay with KB and VERO cell lines.

引用

页码：7539 / 7542

页数：4

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