PLATELET PRESERVATION .2. RESPONSE OF HUMAN PLATELET SUSPENSIONS TO HYPOTONIC STRESS

被引:17
作者
ODINK, J [1 ]
机构
[1] NETHERLANDS RED CROSS BLOOD TRANSF SERV, CENT LAB, AMSTERDAM, NETHERLANDS
关键词
D O I
10.1055/s-0038-1648023
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Platelet suspensions were exposed to hypotonic stress. Several parameters of the changes in light absorbance were investigated i.a. [intra arterially] the initial decrease in absorbance (Amin), the maximal rate of the recovery process (Vmax), and the value of the absorbance 2 h after mixing the platelet suspension with the hypotonic solution. The ratio Vmax/Amin appeared to be independent of both platelet concentration and, within a specific range, decrease in osmolarity. Cryoprotectants appeared to disturb the response to hypotonic stress. Cryopreservation caused a decrease in the light absorbance of the platelet suspension, of Amin, and of the recovery process.
引用
收藏
页码:182 / 191
页数:10
相关论文
共 15 条
[1]  
BASERGA A, 1957, Schweiz Med Wochenschr, V87, P1218
[2]  
BORN GVR, 1972, HUMAN BLOOD COAGULAT, P159
[3]  
FANTL P, 1968, J PHYSIOL-LONDON, V198, P1
[4]  
HANDIN R I, 1970, Transfusion (Bethesda), V10, P305
[5]   STORAGE OF HUMAN-BLOOD PLATELETS - SEROTONIN UPTAKE AND HYPOTONIC SHOCK RESPONSE AS INVITRO VIABILITY TESTS [J].
HARDEMAN, MR ;
HEYNENS, CJL .
THROMBOSIS ET DIATHESIS HAEMORRHAGICA, 1974, 32 (2-3) :405-416
[6]  
HARDEMAN MR, 1975, TRANSFUSION, V15, P231
[7]  
HARDEMAN MR, 1974, THROMB DIATH HAEMOST, V32, P391
[8]  
KAHN RA, 1973, P SOC EXP BIOL MED, V143, P1094
[9]   PLATELET RESPONSE TO HYPOTONIC SHOCK - ITS VALUE AS AN INDICATOR OF PLATELET VIABILITY AFTER STORAGE [J].
KIM, BK ;
BALDINI, MG .
TRANSFUSION, 1974, 14 (02) :130-138
[10]  
KIM BK, 1973, P SOC EXP BIOL MED, V142, P345, DOI 10.3181/00379727-142-37019