EXPRESSION CLONING AND CHARACTERIZATION OF A FUNCTIONAL THROMBIN RECEPTOR REVEALS A NOVEL PROTEOLYTIC MECHANISM OF RECEPTOR ACTIVATION

被引：30

作者：

COUGHLIN, SR ^{[1
]}

VU, TKH ^{[1
]}

HUNG, DT ^{[1
]}

WHEATON, VI ^{[1
]}

机构：

[1] UNIV CALIF SAN FRANCISCO, DEPT MED, SAN FRANCISCO, CA 94143 USA

来源：

SEMINARS IN THROMBOSIS AND HEMOSTASIS | 1992年 / 18卷 / 02期

关键词：

D O I：

10.1055/s-2007-1002422

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：161 / 166

页数：6

共 36 条

[1] MONOCYTE CHEMOTAXIS - STIMULATION BY SPECIFIC EXOSITE REGION IN THROMBIN [J].

BARSHAVIT, R ;

KAHN, A ;

WILNER, GD ;

FENTON, JW .

SCIENCE, 1983, 220 (4598) :728-731

[2] THROMBIN INTERACTIONS WITH PLATELET MEMBRANE-PROTEINS [J].

BERNDT, MC ;

GREGORY, C ;

DOWDEN, G ;

CASTALDI, PA .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1986, 485 :374-386

[3]

BERNDT MC, 1981, PLATELETS BIOL PATHO, P43

[4] THE REFINED 1.9 A CRYSTAL-STRUCTURE OF HUMAN ALPHA-THROMBIN - INTERACTION WITH D-PHE-PRO-ARG CHLOROMETHYLKETONE AND SIGNIFICANCE OF THE TYR-PRO-PRO-TRP INSERTION SEGMENT [J].

BODE, W ;

MAYR, I ;

BAUMANN, U ;

HUBER, R ;

STONE, SR ;

HOFSTEENGE, J .

EMBO JOURNAL, 1989, 8 (11) :3467-3475

[5] TRANSITION OF BOVINE TRYPSINOGEN TO A TRYPSIN-LIKE STATE UPON STRONG LIGAND-BINDING - REFINED CRYSTAL-STRUCTURES OF BOVINE TRYPSINOGEN-PANCREATIC TRYPSIN-INHIBITOR COMPLEX AND OF ITS TERNARY COMPLEX WITH ILE-VAL AT 1.9 A RESOLUTION [J].

BODE, W ;

SCHWAGER, P ;

HUBER, R .

JOURNAL OF MOLECULAR BIOLOGY, 1978, 118 (01) :99-112

[6] MITOGENICITY OF THROMBIN AND SURFACE ALTERATIONS ON MOUSE SPLENOCYTES [J].

CHEN, LB ;

TENG, NNH ;

BUCHANAN, JM .

EXPERIMENTAL CELL RESEARCH, 1976, 101 (01) :41-46

[7] MITOGENIC ACTIVITY OF BLOOD COMPONENTS .1. THROMBIN AND PROTHROMBIN [J].

CHEN, LB ;

BUCHANAN, JM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (01) :131-135

[8]

DANIEL TO, 1986, J BIOL CHEM, V261, P9579

[9] ACTIONS OF THROMBIN AND OTHER COAGULANT AND PROTEOLYTIC ENZYMES ON BLOOD PLATELETS [J].

DAVEY, MG ;

LUSCHER, EF .

NATURE, 1967, 216 (5118) :857-&

[10] THROMBIN IS AN IMPORTANT MEDIATOR OF PLATELET-AGGREGATION IN STENOSED CANINE CORONARY-ARTERIES WITH ENDOTHELIAL INJURY [J].

EIDT, JF ;

ALLISON, P ;

NOBLE, S ;

ASHTON, J ;

GOLINO, P ;

MCNATT, J ;

BUJA, LM ;

WILLERSON, JT .

JOURNAL OF CLINICAL INVESTIGATION, 1989, 84 (01) :18-27

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