SEQUENCE OF A GENE ENCODING BETA-LACTAMASE FROM STREPTOMYCES-CELLULOSAE

被引:10
作者
OGAWARA, H
机构
[1] Department of Biochemistry, Meiji College of Pharmacy, Setagaya-ku, Tokyo
关键词
CLASSIFICATION; EVOLUTION; NADP+; OXACILLIN; BLUE DEXTRAN;
D O I
10.1016/0378-1119(93)90769-Y
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The nucleotide sequence of beta-lactamase (Bla)-encoding gene, bla, from Streptomyces cellulosae KCCS0127 was determined. The deduced amino acid sequence was very close to that of class-A Bla, especially those from Streptomyces species, but completely different from class-D Bla. This is contrary to the result expected from its substrate specificity and its property of binding blue dextran and NADP+.
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页码:111 / 114
页数:4
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