LONG-CHAIN POLYUNSATURATED FATTY-ACIDS AND FETAL GROWTH

被引：97

作者：

LEAF, AA

LEIGHFIELD, MJ

COSTELOE, KL

CRAWFORD, MA

机构：

[1] MED COLL ST BARTHOLOMEW, JOINT ACAD DEPT CHILD HLTH, LONDON EC1A, ENGLAND

[2] HACKNEY HOSP, INST BRAIN CHEM & HUMAN NUTR, LONDON E9, ENGLAND

来源：

EARLY HUMAN DEVELOPMENT | 1992年 / 30卷 / 03期

关键词：

N-6; N-3; LONG CHAIN POLYUNSATURATED FATTY ACIDS; PRETERM INFANT; GROWTH;

D O I：

10.1016/0378-3782(92)90068-R

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Long chain polyunsaturated fatty acid composition of plasma choline phosphoglycerides has been measured at birth in 22 preterm infants. Positive correlations were found between both n-6 and n-3 fatty acids and measurements of growth and maturation. 20:4(n-6) and the sum of 20:3(n-6) + 20:4(n-6) correlated most strongly with weight and head circumference, while 22:6(n-3) showed strongest correlation with length of gestation. These findings are of relevance to understanding the role of nutrition in fetal growth and in establishing the group of infants most at risk of postnatal deficiency of essential fatty acids.

引用

页码：183 / 191

页数：9

共 21 条

[1]

Burr GO, 1930, J BIOL CHEM, V86, P0587

[2]

Burr GO, 1929, J BIOL CHEM, V82, P345

[3] INVITRO FORMATION OF POLY-UNSATURATED FATTY-ACIDS BY DESATURATION IN RAT-BRAIN - SOME PROPERTIES OF ENZYMES IN DEVELOPING BRAIN AND COMPARISONS WITH LIVER [J].

COOK, HW .

JOURNAL OF NEUROCHEMISTRY, 1978, 30 (06) :1327-1334

[4]

Crawford M. A., 1972, Lipids, malnutrition and the developing brain. A Ciba Foundation Symposium jointly with the Nestle Foundation in memory of Sir Norman Wright., P267

[5] N-6 AND N-3 FATTY-ACIDS DURING EARLY HUMAN-DEVELOPMENT [J].