QUANTITATION OF THE ENANTIOMERS OF RIMANTADINE IN HUMAN-PLASMA AND URINE BY GAS CHROMATOGRAPHY-MASS SPECTROMETRY

被引：11

作者：

MIWA, BJ ^{[1
]}

CHOMA, N ^{[1
]}

BROWN, SY ^{[1
]}

KEIGHER, N ^{[1
]}

GARLAND, WA ^{[1
]}

FUKUDA, EK ^{[1
]}

机构：

[1] HOFFMANN LA ROCHE INC,DEPT DRUG METAB,NUTLEY,NJ 07110

来源：

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1988年 / 431卷 / 02期

关键词：

D O I：

10.1016/S0378-4347(00)83102-3

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

引用

页码：343 / 352

页数：10

共 14 条

[1] STEREOCHEMISTRY, A BASIS FOR SOPHISTICATED NONSENSE IN PHARMACOKINETICS AND CLINICAL-PHARMACOLOGY [J].

ARIENS, EJ .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 26 (06) :663-668

[2] FORMATION OF N-GLUCURONIDE OF DESMETHYLIMIPRAMINE IN DOG [J].

BICKEL, MH ;

MINDER, R ;

DIFRANCE.C .

EXPERIENTIA, 1973, 29 (08) :960-961

[3] TOCAINIDE CONJUGATION IN HUMANS - NOVEL BIOTRANSFORMATION PATHWAY FOR A PRIMARY AMINE [J].

ELVIN, AT ;

KEENAGHAN, JB ;

BYRNES, EW ;

TENTHOREY, PA ;

MCMASTER, PD ;

TAKMAN, BH ;

LALKA, D ;

MANION, CV ;

BAER, DT ;

WOLSHIN, EM ;

MEYER, MB ;

RONFELD, RA .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1980, 69 (01) :47-49

[4] QUANTITATIVE-DETERMINATION OF RIMANTADINE IN HUMAN-PLASMA AND URINE BY GC-MS [J].

FUKUDA, EK ;

RODRIGUEZ, LC ;

CHOMA, N ;

KEIGHER, N ;

DEGRAZIA, F ;

GARLAND, WA .

BIOMEDICAL AND ENVIRONMENTAL MASS SPECTROMETRY, 1987, 14 (10) :549-553

[5] QSIMPS - A RESPONSE TO THE ANALYTICAL CHALLENGE OF THE PHARMACOKINETIC REVOLUTION [J].

GARLAND, WA ;

HESS, J ;

BARBALAS, MP .

TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 1986, 5 (06) :132-138

[6] QUANTITATIVE SELECTED ION MONITORING (QSIM) OF DRUGS AND-OR DRUG METABOLITES IN BIOLOGICAL MATRICES [J].

GARLAND, WA ;

POWELL, ML .

JOURNAL OF CHROMATOGRAPHIC SCIENCE, 1981, 19 (08) :392-434

[7]

GIBALDI M, 1975, PHARMACOKINETICS, P36

[8]

MORRISON JD, 1971, ASYMMETRIC ORGANIC R, P50

[9]

PARLI CJ, 1973, DRUG METAB DISPOS, V1, P628

[10] NEW CHIRAL REAGENT FOR DETERMINATION OF ENANTIOMERIC PURITY AND ABSOLUTE CONFIGURATION OF CERTAIN SUBSTITUTED BETA-ARYLETHYLAMINES [J].

POHL, LR ;

TRAGER, WF .

JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (05) :475-479

← 1 2 →