THE SONOGRAPHIC DETECTION OF INTRACRANIAL HEMORRHAGE DUE TO ALLOIMMUNE THROMBOCYTOPENIA

被引：2
作者：
ACKERMAN, B [1 ]
ROUSE, GA [1 ]
DELANGE, M [1 ]
BEDROS, AA [1 ]
SAKALA, EP [1 ]
机构：
[1] LOMA LINDA UNIV,MED CTR,DEPT DIAGNOST ULTRASOUND,LOMA LINDA,CA 92354
来源：
JOURNAL OF DIAGNOSTIC MEDICAL SONOGRAPHY | 1992年 / 8卷 / 05期
关键词：
ALLOIMMUNE THROMBOCYTOPENIA; PLATELET ANTIGENS; ANTIPLATETLET ANTIBODIES; INTRACRANIAL HEMORRHAGE; PORENCEPHALY; SONOGRAPHY; HYDROCEPHALUS;
D O I：
10.1177/875647939200800504
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Alloimmune thrombocytopenia is a rare condition in which antibodies from the mother's circulation cross the placenta and destroy the platelets in the fetus. Approximately 14% of affected fetuses or neonates develop intracranial hemorrhage, leading to death or long-term central nervous system disabilities. After treating two such cases, 26 previously reported cases of alloimmune thrombocytopenia with intracranial hemorrhage were examined to discover if these hemorrhages exhibit a typical sonographic appearance, course, and time of hemorrhage. When intracranial hemorrhage occurs in cases of alloimmune thrombocytopenia, it has a typical appearance in 76% of cases: a large hematoma in the center of the cerebral hemisphere. There is no difference between genders in the occurrence of alloimmune thrombocytopenia unless hemorrhage occurs: 72% of neonates with alloimmune thrombocytopenia and intracranial hemorrhage are male. Intracranial hemorrhage occurs before labor and delivery in 76% of cases. Sonographers cannot depend on a history of the condition in previous pregnancies as an indication of alloimmune thrombocytopenia: only 35% of neonates with alloimmune thrombocytopenia and hemorrhage have previously affected siblings.
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页码：249 / 255
页数：7
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