AN ORTHO-DIRECTING EFFECT IN THE NUCLEOPHILIC AROMATIC-SUBSTITUTION REACTIONS OF PRIMARY AND SECONDARY 2,4-DICHLORO-BENZOAMIDES AND 2,3,4-TRICHLOROBENZAMIDES WITH ETHANETHIOLATE

被引：1
作者：
COOPER, GK
BAKER, DR
BARDEN, LB
机构：
[1] Western Research Center, Zeneca Agricultural Products, Richmond, California
来源：
SYNTHETIC COMMUNICATIONS | 1995年 / 25卷 / 06期
关键词：
D O I：
10.1080/00397919508013427
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reactions of the primary amide and several secondary amides of 2,4-dichloro- and 2,3,4-trichlorobenzoic acid with potassium ethanethiolate in DMF were observed to proceed with a remarkable degree of ortho-regioselectivity. This effect was found to be absent using related tertiary amides as substrates.
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页码：899 / 906
页数：8
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