Postirradiation Osteosarcoma of the Maxilla: A Case Report and Current Review of Literature

被引：14

作者：

Chabchoub, Imene ^{[1
]}

Gharbi, Olfa ^{[1
]}

Remadi, Sami ^{[2
]}

Limem, Sami ^{[1
]}

Trabelsi, Amel ^{[1
]}

Hochlef, Makrem ^{[1
]}

Ben Fatma, Leila ^{[1
]}

Landolsi, Amel ^{[1
]}

Mokni, Moncef ^{[1
]}

Kraiem, Chekib ^{[1
]}

Ben Ahmed, Slim ^{[1
]}

机构：

[1] Univ Hosp Farhat Hached, Dept Med Oncol, Sousse 4000, Tunisia

[2] Univ Med, Dept Pathol, Sousse 4000, Tunisia

来源：

JOURNAL OF ONCOLOGY | 2009年 / 2009卷

关键词：

D O I：

10.1155/2009/876138

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background. Radiation-induced sarcomas are well-known potential late sequelae of radiation therapy. They are of rare occurrence in jaw bones and are even rarer in the maxilla. Case report. We report a case of radiation-induced osteosarcoma involving the maxilla in a patient treated with radiotherapy for nasopharyngeal carcinoma 14 years ago. Despite neoadjuvant chemotherapy, surgical treatment could not be performed, and the patient received palliative chemotherapy. Conclusions. Radiation-induced osteosarcomas are aggressive and often elude early detection and timely intervention, rapidly leading to early demise of afflicted patients. Long-term patient follow-up and a high index of suspicion are crucial for timely intervention. Copyright (C) 2009 Imene Chabchoub et al.

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