Postirradiation Osteosarcoma of the Maxilla: A Case Report and Current Review of Literature

被引:14
作者
Chabchoub, Imene [1 ]
Gharbi, Olfa [1 ]
Remadi, Sami [2 ]
Limem, Sami [1 ]
Trabelsi, Amel [1 ]
Hochlef, Makrem [1 ]
Ben Fatma, Leila [1 ]
Landolsi, Amel [1 ]
Mokni, Moncef [1 ]
Kraiem, Chekib [1 ]
Ben Ahmed, Slim [1 ]
机构
[1] Univ Hosp Farhat Hached, Dept Med Oncol, Sousse 4000, Tunisia
[2] Univ Med, Dept Pathol, Sousse 4000, Tunisia
关键词
D O I
10.1155/2009/876138
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background. Radiation-induced sarcomas are well-known potential late sequelae of radiation therapy. They are of rare occurrence in jaw bones and are even rarer in the maxilla. Case report. We report a case of radiation-induced osteosarcoma involving the maxilla in a patient treated with radiotherapy for nasopharyngeal carcinoma 14 years ago. Despite neoadjuvant chemotherapy, surgical treatment could not be performed, and the patient received palliative chemotherapy. Conclusions. Radiation-induced osteosarcomas are aggressive and often elude early detection and timely intervention, rapidly leading to early demise of afflicted patients. Long-term patient follow-up and a high index of suspicion are crucial for timely intervention. Copyright (C) 2009 Imene Chabchoub et al.
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页数:4
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