2 ADDITIONAL CASES OF ISOCHROMOSOME 21Q OR TRANSLOCATION 21Q21Q IN HEMATOLOGICAL MALIGNANCIES

被引：10
作者：
HURET, JL
SCHOENWALD, M
GABARRE, J
VAUGIER, GL
TANZER, J
机构：
[1] CNRS,URA 1338,F-86022 POITIERS,FRANCE
[2] HOP LA PITIE SALPETRIERE,PARIS,FRANCE
来源：
ACTA HAEMATOLOGICA | 1991年 / 86卷 / 02期
关键词：
ISOCHROMOSOME; 21Q; LEUKEMIAS; TRANSLOCATION; 21Q21Q;
D O I：
10.1159/000204815
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report on 2 patients with isochromosome 21q [i(21q)] or translocation 21q21q [t(21q21q)] in myeloid disorders. Of 18 available cases of i(21q) or t(21q21q), 15 were found in myeloid malignancies, often secondary to a previous carcinogen exposure. Complex karyotypes were found in most cases. Four cases presented with i(21q) or t(21q21q) as the sole anomaly, and this might represent a specific entity.
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收藏
页码：111 / 114
页数：4
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