2 ADDITIONAL CASES OF ISOCHROMOSOME 21Q OR TRANSLOCATION 21Q21Q IN HEMATOLOGICAL MALIGNANCIES

被引:10
作者
HURET, JL
SCHOENWALD, M
GABARRE, J
VAUGIER, GL
TANZER, J
机构
[1] CNRS,URA 1338,F-86022 POITIERS,FRANCE
[2] HOP LA PITIE SALPETRIERE,PARIS,FRANCE
关键词
ISOCHROMOSOME; 21Q; LEUKEMIAS; TRANSLOCATION; 21Q21Q;
D O I
10.1159/000204815
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We report on 2 patients with isochromosome 21q [i(21q)] or translocation 21q21q [t(21q21q)] in myeloid disorders. Of 18 available cases of i(21q) or t(21q21q), 15 were found in myeloid malignancies, often secondary to a previous carcinogen exposure. Complex karyotypes were found in most cases. Four cases presented with i(21q) or t(21q21q) as the sole anomaly, and this might represent a specific entity.
引用
收藏
页码:111 / 114
页数:4
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