2 ADDITIONAL CASES OF ISOCHROMOSOME 21Q OR TRANSLOCATION 21Q21Q IN HEMATOLOGICAL MALIGNANCIES

被引：10

作者：

HURET, JL

SCHOENWALD, M

GABARRE, J

VAUGIER, GL

TANZER, J

机构：

[1] CNRS,URA 1338,F-86022 POITIERS,FRANCE

[2] HOP LA PITIE SALPETRIERE,PARIS,FRANCE

来源：

ACTA HAEMATOLOGICA | 1991年 / 86卷 / 02期

关键词：

ISOCHROMOSOME; 21Q; LEUKEMIAS; TRANSLOCATION; 21Q21Q;

D O I：

10.1159/000204815

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report on 2 patients with isochromosome 21q [i(21q)] or translocation 21q21q [t(21q21q)] in myeloid disorders. Of 18 available cases of i(21q) or t(21q21q), 15 were found in myeloid malignancies, often secondary to a previous carcinogen exposure. Complex karyotypes were found in most cases. Four cases presented with i(21q) or t(21q21q) as the sole anomaly, and this might represent a specific entity.

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页码：111 / 114

页数：4

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