I-131 ROSE-BENGAL THERAPY IN HEPATOBLASTOMA PATIENTS

被引：0
|
作者：
DEKRAKER, J [1 ]
HOEFNAGEL, CA [1 ]
VOUTE, PA [1 ]
机构：
[1] ANTONI VAN LEEUWENHOEK HOSP,NETHERLANDS CANC INST,DEPT NUCL MED,AMSTERDAM,NETHERLANDS
来源：
EUROPEAN JOURNAL OF CANCER | 1991年 / 27卷 / 05期
关键词：
D O I：
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中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
If conventional treatment modalities have failed in hepatoblastoma patients and no distant metastases can be demonstrated therapy with radionuclide agents can be considered. In 6 patients diagnostic technetium-99m (Tc-99m)-disofenin and two iodine-131 (I-131)-rose bengal scans were made. 2 patients demonstrated specific uptake of disofenin. One of these had a positive scintigram with radiolabelled rose bengal. This patient was subsequently treated with 1.1 GB(q) I-131-rose bengal. No toxicity was observed. A clear decrease in the level of alpha-fetoprotein indicated a response and demonstrated that this radiopharmaceutical can be used for tumour targeted radiation therapy in selected patients with therapy resistant tumours.
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页码：613 / 615
页数：3
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