THE HEPATOTOXICITY OF VALPROIC ACID AND ITS METABOLITES IN RATS .2. INTERMEDIARY AND VALPROIC ACID METABOLISM

被引：80
|
作者：
GRANNEMAN, GR [1 ]
WANG, SI [1 ]
KESTERSON, JW [1 ]
MACHINIST, JM [1 ]
机构：
[1] ABBOTT LABS, DIV PHARMACEUT PROD, DIV DRUG SAFETY EVALUAT, N CHICAGO, IL 60064 USA
来源：
HEPATOLOGY | 1984年 / 4卷 / 06期
关键词：
D O I：
10.1002/hep.1840040610
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：1153 / 1158
页数：6
相关论文
共 50 条
  • [1] THE ROLE OF TOXIC METABOLITES IN THE HEPATOTOXICITY OF VALPROIC ACID
    KINGSLEY, E
    TWEEDALE, R
    GRAY, P
    TOLMAN, KG
    GASTROENTEROLOGY, 1980, 79 (05) : 1031 - 1031
  • [2] HEPATOTOXICITY OF VALPROIC ACID
    SUSSMAN, NM
    MCLAIN, LW
    LEPPIK, IE
    NEUROLOGY, 1979, 29 (04) : 601 - 601
  • [3] THE HEPATOTOXICITY OF VALPROIC ACID AND ITS METABOLITES IN RATS .1. TOXICOLOGIC, BIOCHEMICAL AND HISTOPATHOLOGIC STUDIES
    KESTERSON, JW
    GRANNEMAN, GR
    MACHINIST, JM
    HEPATOLOGY, 1984, 4 (06) : 1143 - 1152
  • [4] FATAL VALPROIC ACID (VPA) HEPATOTOXICITY
    TAYLOR, DA
    DESCHRYVER, K
    KEATING, JP
    PRENSKY, AL
    DODSON, WE
    DOVE, DJ
    PEDIATRIC RESEARCH, 1981, 15 (04) : 712 - 712
  • [5] THE EFFECT OF CARBAMAZEPINE ON VALPROIC ACID AND ITS UNSATURATED METABOLITES
    FARRELL, K
    PANESAR, S
    ORR, JM
    BURTON, R
    ABBOTT, FS
    ANNALS OF NEUROLOGY, 1987, 22 (03) : 418 - 418
  • [6] MITOCHONDRIAL METABOLISM OF VALPROIC ACID
    LI, JX
    NORWOOD, DL
    MAO, LF
    SCHULZ, H
    BIOCHEMISTRY, 1991, 30 (02) : 388 - 394
  • [7] ASPECTS OF THE METABOLISM OF VALPROIC ACID
    GRANNEMAN, GR
    WANG, SI
    MACHINIST, JM
    KESTERSON, JW
    XENOBIOTICA, 1984, 14 (05) : 375 - 387
  • [8] LACK OF TERATOGENICITY OF TRANS-2-ENE-VALPROIC ACID COMPARED TO VALPROIC ACID IN RATS
    VORHEES, CV
    ACUFFSMITH, KD
    WEISENBURGER, WP
    MINCK, DR
    BERRY, JS
    SETCHELL, KDR
    NAU, H
    TERATOLOGY, 1991, 43 (06) : 583 - 590
  • [9] ACUTE VALPROIC ACID OVERDOSE - CLINICAL COURSE AND PHARMACOKINETIC DISPOSITION OF VALPROIC ACID AND METABOLITES
    DUPUIS, RE
    LICHTMAN, SN
    POLLACK, GM
    DRUG SAFETY, 1990, 5 (01) : 65 - 71
  • [10] Protective effects of naringin on valproic acid-induced hepatotoxicity in rats
    Koroglu, Omer Faruk
    Gunata, Mehmet
    Vardi, Nigar
    Yildiz, Azibe
    Ates, Burhan
    Colak, Cemil
    Tanriverdi, Lokman Hekim
    Parlakpinar, Hakan
    TISSUE & CELL, 2021, 72
12345