TREATMENT OF INTRACTABLE GASTROINTESTINAL MANIFESTATIONS OF CHRONIC GRANULOMATOUS-DISEASE WITH CYCLOSPORINE

被引：44

作者：

ROSH, JR

TANG, HB

MAYER, L

GROISMAN, G

ABRAHAM, SK

PRINCE, A

机构：

[1] COLUMBIA UNIV, COLL PHYS & SURG, DIV INFECT DIS, NEW YORK, NY 10031 USA

[2] CUNY MT SINAI SCH MED, DEPT PEDIAT, NEW YORK, NY 10029 USA

[3] CUNY MT SINAI SCH MED, DEPT MED, NEW YORK, NY 10029 USA

[4] CUNY MT SINAI SCH MED, DEPT PATHOL, NEW YORK, NY 10029 USA

来源：

JOURNAL OF PEDIATRICS | 1995年 / 126卷 / 01期

关键词：

D O I：

10.1016/S0022-3476(95)70519-8

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Gastrointestinal manifestations of chronic granulomatous disease of childhood include granulomatous inflammatory bowel disease, Severe colitis and perirectal disease developed in a 12-year-old boy with chronic granulomatous disease while he was receiving interferon gamma therapy, The boy had a deficiency of the 22 kd light chain of the cytochrome b heterodimer. After conventional medical therapy proved to be ineffective, a rapid clinical response was obtained to cyclosporine.

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页码：143 / 145

页数：3

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