ARYLLEAD-MEDIATED SYNTHESIS OF LINEAR 3-ARYLPYRANOCOUMARINS - SYNTHESIS OF ROBUSTIN AND ROBUSTIC ACID

被引：22

作者：

DONNELLY, DMX ^{[1
]}

MOLLOY, DJ ^{[1
]}

REILLY, JP ^{[1
]}

FINET, JP ^{[1
]}

机构：

[1] FAC SCI & TECH ST JEROME,CNRS,URA 1412,F-13397 MARSEILLE 20,FRANCE

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1995年 / 20期

关键词：

D O I：

10.1039/p19950002531

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The two naturally occurring linear 3-arylpyranocoumarins, robustin 1 and robustic acid ?, have been synthesised in nine steps from methyl 2,4,6-trihydroxyphenyl ketone, in 19% overall yield for robustin and 18% for robustic acid. Their syntheses involved, as a key step, the regioselective arylation of a functionalised 4-hydroxybenzo [1,2-b:5,4-b']dipyran-2-one with the appropriate aryllead triacetate.

引用

页码：2531 / 2534

页数：4

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