THE EFFECT OF A LOW ESSENTIAL FATTY-ACID DIET ON HIBERNATION IN MARMOTS

被引:86
作者
FLORANT, GL [1 ]
HESTER, L [1 ]
AMEENUDDIN, S [1 ]
RINTOUL, DA [1 ]
机构
[1] KANSAS STATE UNIV AGR & APPL SCI,DIV BIOL,MANHATTAN,KS 66506
来源
AMERICAN JOURNAL OF PHYSIOLOGY | 1993年 / 264卷 / 04期
关键词
LIPID; LIPOLYSIS; BODY TEMPERATURE;
D O I
10.1152/ajpregu.1993.264.4.R747
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
We investigated the effect of an essential fatty acid (EFA)-deficient diet on hibernation patterns in yellow-bellied marmots (Marmota flaviventris). Fatty acid (FA) analysis of white adipose tissue (WAT) from animals maintained for 2 mo on the EFA-deficient diet suggested that little or no EFAs were present in the gonadal or omental fat depots. Hibernation bout lengths of the EFA-deficient animals were significantly shorter (P < 0.01) than control animals. Stated another way, these animals aroused twice as frequently compared with control animals and used more energy to survive winter. Analysis of WAT composition and blood samples revealed that animals were highly lipolytic during winter. Furthermore, the release of FAs was not random: linoleate (cis-9,cis-12-octadecadienoic acid; 18:2, a diene EFA) was significantly (P < 0.05) under-represented in venous outflow from the gonadal WAT pad based on the percentage of this species in WAT. The concentration of saturated FAs was higher than that predicted from the WAT-FA composition. We conclude that linoleate is preferrentially retained within WAT and that concentrations of this EFA may influence hibernation behavior. Thus EFAs may have a thermoregulatory role in hibernation in addition to their role as essential precursors for physiologically important lipids after hibernation is over.
引用
收藏
页码:R747 / R753
页数:7
相关论文
共 50 条
[41]   Climate regime shifts and reorganization of fish communities: the essential fatty acid limitation hypothesis [J].
Litzow, Michael A. ;
Bailey, Kevin M. ;
Prahl, Fredrick G. ;
Heintz, Ron .
MARINE ECOLOGY PROGRESS SERIES, 2006, 315 :1-11
[42]   Comparison of blood leptin and vitamin E and blood and adipose fatty acid compositions in wild and captive populations of critically endangered Vancouver Island marmots (Marmota vancouverensis) [J].
Aymen, Jessica ;
Delnatte, Pauline ;
Beaufrere, Hugues ;
Chalil, Dan ;
Steckel, Klaudia E. ;
Gourlie, Sarra ;
Stark, Ken D. ;
McAdie, Malcolm .
ZOO BIOLOGY, 2023, 42 (02) :308-321
[43]   SEX DIFFERENCE IN TRIGLYCERIDE FATTY-ACID SUBSTRATE CYCLING OF RAT ADIPOSE-TISSUE - INDIRECT REGULATION BY ANDROGENS [J].
HANSSON, P ;
SAGGERSON, D ;
NILSSONEHLE, P .
HORMONE AND METABOLIC RESEARCH, 1991, 23 (10) :465-468
[44]   CHANGES OF LIPID, PROTEIN, RNA AND FATTY-ACID COMPOSITION IN DEVELOPING SESAME (SESAMUM-INDICUM L) SEEDS [J].
CHUNG, CH ;
YEE, YJ ;
KIM, DH ;
KIM, HK ;
CHUNG, DS .
PLANT SCIENCE, 1995, 109 (02) :237-243
[45]   FATTY-ACID PROFILES OF LIPID DEPOTS AND CHOLESTEROL CONCENTRATION IN MUSCLE-TISSUE OF FINISHING PIGS FED RACTOPAMINE [J].
ENGESETH, NJ ;
LEE, KO ;
BERGEN, WG ;
HELFERICH, WG ;
KNUDSON, BK ;
MERKEL, RA .
JOURNAL OF FOOD SCIENCE, 1992, 57 (05) :1060-1062
[46]   Is there an optimal dose for dietary linoleic acid? Lessons from essential fatty acid deficiency supplementation and adipocyte functions in rats [J].
Isabelle Harant-Farrugia ;
Jésus Garcia ;
Mari-Carmen Iglesias-Osma ;
Maria José Garcia-Barrado ;
Christian Carpéné .
Journal of Physiology and Biochemistry, 2014, 70 :615-627
[47]   Effect of low-cost substrate on the fatty acid profiles of Mortierella alpina CBS 754.68 and Wickerhamomyces siamensis SAKSG [J].
Samadlouie, Hamid Reza ;
Nurmohamadi, Sanaz ;
Moradpoor, Fatemeh ;
Gharanjik, Shahrokh .
BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT, 2018, 32 (05) :1228-1235
[48]   Is there an optimal dose for dietary linoleic acid? Lessons from essential fatty acid deficiency supplementation and adipocyte functions in rats [J].
Harant-Farrugia, Isabelle ;
Garcia, Jesus ;
Iglesias-Osma, Mari-Carmen ;
Jose Garcia-Barrado, Maria ;
Carpene, Christian .
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2014, 70 (02) :615-627
[49]   Essential fatty acid deficiency in parenteral nutrition: Historical perspective and modern solutions, a narrative review [J].
Wolff, Jodi ;
Cober, Mary Petrea ;
Huff, Katie A. .
NUTRITION IN CLINICAL PRACTICE, 2025, 40 (02) :350-367
[50]   The effects of forskolin and rolipram on cAMP, cGMP and free fatty acid levels in diet induced obesity [J].
Doseyici, S. ;
Mehmetoglu, I. ;
Toker, A. ;
Yerlikaya, F. H. ;
Erbay, E. .
BIOTECHNIC & HISTOCHEMISTRY, 2014, 89 (05) :388-392