CEREBROSPINAL-FLUID SOMATOSTATIN CONCENTRATIONS IN SCHIZOPHRENIA AND SCHIZOAFFECTIVE DISORDER - THE EFFECTS OF ANTIPSYCHOTIC TREATMENT

被引：6
作者：
SHARMA, RP
BISSETTE, G
JANICAK, P
DAVIS, JM
NEMEROFF, CB
机构：
[1] ILLINOIS STATE PSYCHIAT INST, CHICAGO, IL 60651 USA
[2] DUKE UNIV, MED CTR, DURHAM, NC USA
[3] EMORY UNIV, SCH MED, DEPT PSYCHIAT & BEHAV SCI, ATLANTA, GA USA
来源：
SCHIZOPHRENIA RESEARCH | 1994年 / 13卷 / 02期
关键词：
SOMATOSTATIN; ANTIPSYCHOTIC; HOMOVANILLIC ACID;
D O I：
10.1016/0920-9964(94)90099-X
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
The authors examined the effects of antipsychotic treatment on cerebrospinal fluid somatostatin like immunoreactivity (CSF SLI) in 14 schizophrenic and 3 schizoaffective patients. There was a modest but significant increase in CSF SLI in 13 out of the 14 schizophrenic patients. In addition, there was a significant positive correlation between duration of treatment and post-treatment CSF SLI concentrations. No differential response was noted in patients also treated with the anticholinergic benztropine.
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收藏
页码：173 / 177
页数：5
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