INTERACTION BETWEEN DIVERSE SYNTHETIC POLYPEPTIDES IN AQUEOUS-SOLUTION

Inferaction between water soluble diverse, synthetic, polypeptides in aqueous solution was studied by circular dichroism (CD) spectra. The interaction was evaluated from the significant difference between minimum of maximum peaks of CD spectra in ellipticity for mixed solution of two peptides and mean ellipticity of the each peptide. The minimum peak of a mixture for poly(Ala, Pro) ; A with Poly(Ala, Asp) ; B, or Poly(Ala, Lys) ; C, respectively, was less than the mean value of those of A and B or A and C. The minimum peak of polyproline ; D with B was less than the mean value of that of D with C. While, the CD pattern of the mixture of poly(Ala, Asp) ; A, with poly(Gly, Pro) ; E or poly(Ala, DL-Trp) ; F, respectively, was accordance with average of those A and E or A and F.