Automated Diagnosis of Otitis Media: Vocabulary and Grammar

被引:42
作者
Kuruvilla, Anupama [1 ,2 ]
Shaikh, Nader [3 ]
Hoberman, Alejandro [3 ]
KovaIevic, Jelena [1 ,2 ,4 ]
机构
[1] Carnegie Mellon Univ, Dept BME, Pittsburgh, PA 15213 USA
[2] Carnegie Mellon Univ, Ctr Bioimage Informat, Pittsburgh, PA 15213 USA
[3] Univ Pittsburgh Sch Med, Childrens Hosp Pittsburgh, Div Gen Acad Pediat, Pittsburgh, PA 15213 USA
[4] Carnegie Mellon Univ, Dept ECE, Pittsburgh, PA 15213 USA
关键词
D O I
10.1155/2013/327515
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
We propose a novel automated algorithm for classifying diagnostic categories of otitis media: acute otitis media, otitis media with effusion, and no effusion. Acute otitis media represents a bacterial superinfection of the middle ear fluid, while otitis media with effusion represents a sterile effusion that tends to subside spontaneously. Diagnosing children with acute otitis media is difficult, often leading to overprescription of antibiotics as they are beneficial only for children with acute otitis media. This underscores the need for an accurate and automated diagnostic algorithm. To that end, we design a feature set understood by both otoscopists and engineers based on the actual visual cues used by otoscopists; we term this the otitis media vocabulary. We also design a process to combine the vocabulary terms based on the decision process used by otoscopists; we term this the otitis media grammar. The algorithm achieves 89.9% classification accuracy, outperforming both clinicians who did not receive special training and state-of-the- art classifiers.
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页数:15
相关论文
共 43 条
[1]  
Asher E, 2005, ACTA PAEDIATR, V94, P423, DOI [10.1080/08035250410023674, 10.1111/j.1651-2227.2005.tb01912.x]
[2]   Color constancy for scenes with varying illumination [J].
Barnard, K ;
Finlayson, G ;
Funt, B .
COMPUTER VISION AND IMAGE UNDERSTANDING, 1997, 65 (02) :311-321
[3]   What is the set of images of an object under all possible lighting conditions? [J].
Belhumeur, PN ;
Kriegman, DJ .
1996 IEEE COMPUTER SOCIETY CONFERENCE ON COMPUTER VISION AND PATTERN RECOGNITION, PROCEEDINGS, 1996, :270-277
[4]   AUTOMATIC IDENTIFICATION AND DELINEATION OF GERM LAYER COMPONENTS IN H&E STAINED IMAGES OF TERATOMAS DERIVED FROM HUMAN AND NONHUMAN PRIMATE EMBRYONIC STEM CELLS [J].
Bhagavatula, Ramamurthy ;
Fickus, Matthew ;
Kelly, W. ;
Guo, Chenlei ;
Ozolek, John A. ;
Castro, Carlos A. ;
Kovacevic, Jelena .
2010 7TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: FROM NANO TO MACRO, 2010, :1041-1044
[5]  
Bornard Raphael, 2002, P 10 ACM INT C MULTI, P355, DOI DOI 10.1145/641007.641084
[6]   Random forests [J].
Breiman, L .
MACHINE LEARNING, 2001, 45 (01) :5-32
[7]   Recognition of paediatric otopathology by General Practitioners [J].
Buchanan, Carolyn M. ;
Pothier, David D. .
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2008, 72 (05) :669-673
[8]  
Canny J., 1986, IEEE T PATTERN ANAL, V8, P1293
[9]   LIBSVM: A Library for Support Vector Machines [J].
Chang, Chih-Chung ;
Lin, Chih-Jen .
ACM TRANSACTIONS ON INTELLIGENT SYSTEMS AND TECHNOLOGY, 2011, 2 (03)
[10]   A multiresolution approach to automated classification of protein subcellular location images [J].
Chebira, Amina ;
Barbotin, Yann ;
Jackson, Charles ;
Merryman, Thomas ;
Srinivasa, Gowri ;
Murphy, Robert F. ;
Kovacevic, Jelena .
BMC BIOINFORMATICS, 2007, 8 (1)