INCORPORATION OF A PYRENE NUCLEOSIDE ANALOG INTO SYNTHETIC OLIGODEOXYNUCLEOTIDES USING A NUCLEOSIDE-LIKE SYNTHON

被引:20
作者
PROKHORENKO, IA
KORSHUN, VA
PETROV, AA
GONTAREV, SV
BERLIN, YA
机构
[1] SMEYAKIN OVCHINNIKOV BIOORGAN CHEM INST, MOSCOW 117871, RUSSIA
[2] BYELORUSSIAN MINIST HLTH, BYELORUSSIAN RES INST EPIDEMIOL & MICROBIOL, MINSK 220050, BELARUS
关键词
D O I
10.1016/0960-894X(95)00373-2
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A novel phosphoramidite 4 based on the hydroxyprolinol 1 backbone has been synthesized and used to chemically prepare DNA fragments bearing a pyrene-containing nucleoside analogue.
引用
收藏
页码:2081 / 2084
页数:4
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