DIFFERENTIAL BLOCKADE OF MUSCARINIC RECEPTOR SUBTYPES BY POLYMETHYLENE TETRAAMINES - NOVEL CLASS OF SELECTIVE ANTAGONISTS OF CARDIAC M-2 MUSCARINIC RECEPTORS

被引：154
作者：
MELCHIORRE, C
CASSINELLI, A
QUAGLIA, W
机构：
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1987年 / 30卷 / 01期
关键词：
D O I：
10.1021/jm00384a034
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：201 / 204
页数：4
相关论文
共 21 条
[1]   STRUCTURE ACTIVITY RELATIONSHIPS AMONG BENEXTRAMINE-RELATED TETRAAMINE DISULFIDES AT PERIPHERAL ALPHA-ADRENORECEPTORS [J].
ANGELI, P ;
BRASILI, L ;
BRANCIA, E ;
GIARDINA, D ;
QUAGLIA, W ;
MELCHIORRE, C .
JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (11) :1643-1647
[2]   SOME QUANTITATIVE USES OF DRUG ANTAGONISTS [J].
ARUNLAKSHANA, O ;
SCHILD, HO .
BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1959, 14 (01) :48-58
[3]   A SEARCH FOR SELECTIVE ANTAGONISTS AT M2-MUSCARINIC RECEPTORS [J].
BARLOW, RB ;
SHEPHERD, MK .
BRITISH JOURNAL OF PHARMACOLOGY, 1985, 85 (02) :427-435
[4]   THE ACTIONS OF SOME ESTERS OF 4-HYDROXYQUINUCLIDINE ON GUINEA-PIG ILEUM, ATRIA AND RAT FUNDUS STRIP [J].
BARLOW, RB ;
KITCHEN, R .
BRITISH JOURNAL OF PHARMACOLOGY, 1982, 77 (03) :549-557
[5]   IRREVERSIBLE ALPHA-ADRENOCEPTOR BLOCKING EFFECTS AND REVERSIBLE MUSCARINIC BLOCKING AND NICOTINIC BLOCKING EFFECTS OF TETRAMINE DISULFIDES ON THE HEART [J].
BENFEY, BG ;
BELLEAU, B ;
BRASILI, L ;
GIANNELLA, M ;
MELCHIORRE, C .
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1980, 58 (12) :1477-1483
[6]   POTENTIATION AND INHIBITION OF NICOTINIC EFFECTS ON STRIATED-MUSCLE BY THE TETRAMINE DISULFIDE BENEXTRAMINE [J].
BENFEY, BG ;
BRASILI, L ;
MELCHIORRE, C ;
BELLEAU, B .
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1980, 58 (08) :984-988
[7]   CARDIAC MUSCARINIC BLOCKING AND ATROPINIC BLOCKING EFFECTS OF A TETRAMINE DISULFIDE WITH ALPHA-ADRENOCEPTOR BLOCKING ACTIVITY [J].
BENFEY, BG ;
YONG, MS ;
BELLEAU, B ;
MELCHIORRE, C .
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1979, 57 (01) :41-47
[8]   MUSCARINIC RECEPTOR SUBCLASSES [J].
BIRDSALL, NJM ;
HULME, EC .
TRENDS IN PHARMACOLOGICAL SCIENCES, 1983, 4 (11) :459-463
[9]   FAILURE OF GALLAMINE AND PANCURONIUM TO INHIBIT SELECTIVELY (-)-[H-3]QUINUCLIDINYL BENZILATE BINDING IN GUINEA-PIG ATRIA [J].
CHOO, LK ;
LEUNG, E ;
MITCHELSON, F .
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1985, 63 (03) :200-208
[10]   INHIBITORY EFFECT OF GALLAMINE ON MUSCARINIC RECEPTORS [J].
CLARK, AL ;
MITCHELSON, F .
BRITISH JOURNAL OF PHARMACOLOGY, 1976, 58 (03) :323-331
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