DAILY CHANGES IN PENTYLENETETRAZOL-INDUCED CONVULSIONS AND OPEN-FIELD BEHAVIOR IN RATS

被引：28

作者：

EIDMAN, DS ^{[1
]}

BENEDITO, MAC ^{[1
]}

LEITE, JR ^{[1
]}

机构：

[1] ESCOLA PAULISTA MED SCH,DEPT PSICOBIOL,RUA BOTUCATU 862,CP 20399,BR-04034 SAO PAULO,SP,BRAZIL

来源：

PHYSIOLOGY & BEHAVIOR | 1990年 / 47卷 / 05期

关键词：

Convulsions; Daily variation; Open-field behavior; Pentylenetetrazol;

D O I：

10.1016/0031-9384(90)90008-R

中图分类号：

B84 [心理学];

学科分类号：

04 ; 0402 ;

摘要：

Susceptibility to pentylenetetrazol (PTZ)-induced clonic convulsions was measured in rats over the 24-hr light-dark cycle at four-hour intervals. The results showed a higher sensitivity to PTZ around 2200 hr. Other groups of rats were exposed to a four-min open-field session. In the first two min of the session the animals were submitted to open-field environmental stimuli. The next two-min observation occurred with sound and light presented to the animals. Differences through the 24-hr period of the day for both sessions were seen. A reduction in rearing at 2200 hr and increase in defecation at 2200 hr and 0200 hr was observed. © 1990.

引用

页码：853 / 856

页数：4

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