POST-TONSILLECTOMY INFILTRATION WITH BUPIVACAINE REDUCES IMMEDIATE POSTOPERATIVE PAIN IN CHILDREN

被引:40
作者
WONG, AK
BISSONNETTE, B
BRAUDE, BM
MACDONALD, RM
FEAR, DW
机构
[1] UNIV TORONTO,HOSP SICK CHILDREN,DEPT ANAESTHESIA,TORONTO,ON M5G 1X8,CANADA
[2] UNIV TORONTO,HOSP SICK CHILDREN,DEPT OTORHINOLARYNGOL,TORONTO,ON M5G 1X8,CANADA
[3] UNIV TORONTO,HOSP SICK CHILDREN,DEPT CLIN BIOCHEM,TORONTO,ON M5G 1X8,CANADA
来源
CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE | 1995年 / 42卷 / 09期
关键词
ANESTHETICS; LOCAL; BUPIVACAINE; ANESTHESIA; PEDIATRIC; PAIN; POSTOPERATIVE; SURGERY; ENT; TONSILLECTOMY;
D O I
10.1007/BF03011174
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Pain management after tonsillectomy in children remains a dilemma for the anaesthetist. A previous study demonstrated that the administration of lidocaine 1% topical spray to the peritonsillar fossae before tracheal extubation provided considerable immediate postoperative pain relief in infants and children. However, the pain relief was of short duration. We were hopeful that the use of bupivacaine would offer more prolonged pain relief because of its pharmacological characteristics. Therefore, this study was designed to compare the effects of bupivacaine 0.5% with 1:200,000 epinephrine administered after tonsillectomy either as topical spray or submucosal infiltration on postoperative pain in children. Forty-three patients aged two to ten years were randomized into three groups after tonsillectomy was performed. Group (1) received 0.5 ml . kg(-1) normal saline spray; (2) received 2 mg . kg(-1) bupivacaine 0.5% with 1:200,000 epinephrine peritonsillar infiltration in a similar volume to Group 1 and (3) received 2 mg . kg(-1) bupivacaine 0.5% with 1:200,000 epinephrine spray to both tonsillar beds. The patients in each group were compared postoperatively with regard to the quality of pain control using the Objective Pain Score, and their analgesic requirements. Peritonsillar infiltration of bupivacaine provided superior immediate postoperative analgesia as reflected by lower recovery room pain scores (P < 0.05) and opioid requirements (P < 001). Ward pain scores and analgesic requirements were similar among groups. Peritonsillar infiltration of bupivacaine 0.5% with 1:200,000 epinephrine provides better post-tonsillectomy pain control in the immediate postoperative period than bupivacaine spray or placebo.
引用
收藏
页码:770 / 774
页数:5
相关论文
共 16 条
[1]   LOCAL VERSUS GENERAL-ANESTHESIA IN TONSILLECTOMY [J].
AGREN, K ;
ENGQUIST, S ;
DANNEMAN, A ;
FEYCHTING, B .
CLINICAL OTOLARYNGOLOGY, 1989, 14 (02) :97-100
[2]  
ALLEN RT, 1953, AMA ARCH OTOLARYNGOL, V57, P86
[3]   LIDOCAINE IN AEROSOL FORM FOR THE TONSILLECTOMIZED CHILD [J].
BISSONNETTE, B .
CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 1990, 37 (05) :534-537
[4]  
GIBBS P, 1987, ANN ROY COLL SURG, V69, P189
[5]  
HARTLEY EJ, 1991, ANESTH ANALG, V73, P29
[6]  
HOPE JW, 1954, AM J ROENTGENOL, V71, P251
[7]   THE EFFECT OF PRE-INCISIONAL INFILTRATION OF TONSILS WITH BUPIVACAINE ON THE PAIN FOLLOWING TONSILLECTOMY UNDER GENERAL-ANESTHESIA [J].
JEBELES, JA ;
REILLY, JS ;
GUTIERREZ, JF ;
BRADLEY, EL ;
KISSIN, I .
PAIN, 1991, 47 (03) :305-308
[8]  
KATZ J, 1992, ANESTHESIOLOGY, V27, P439
[9]  
KING J T, 1963, Laryngoscope, V73, P466
[10]  
Norden J, 1991, ANESTH ANALG, V72, pS199