EXPRESSION OF MHC CLASS-I ANTIGEN IN MORRIS RAT HEPATOMA AND NORMAL LIVER

被引：1
|
作者：
WANG, DF
YANG, EB
MACH, P
CHENG, LY
机构：
[1] NATL UNIV SINGAPORE,FAC MED,DEPT BIOCHEM,SINGAPORE 0511,SINGAPORE
[2] SINGAPORE GEN HOSP,DEPT SURG,SINGAPORE 0316,SINGAPORE
来源：
CANCER LETTERS | 1994年 / 84卷 / 01期
关键词：
MORRIS HEPATOMA; MHC CLASS I ANTIGEN; BUFFALO RAT;
D O I：
10.1016/0304-3835(94)90357-3
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Expression of major histocompatibility complex (MHC) class I antigen in Morris rat;hepatoma 7777 and normal rat liver tissues was studied by immunohistochemical techniques, Western blot and radiobinding assay. It was found that hepatoma tissue displayed a pattern of enhanced MHC class I antigen expression compared with normal liver. This phenomenon may represent an uncommon pattern of MHC class I antigen expression of liver tumor. The influence of enhanced MHC class I antigen expression on the development and spread of tumors as well as the possible mechanisms of this enhancement are discussed.
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页码：51 / 57
页数：7
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