DOSE DISTRIBUTIONS AND DOSE-RATE CONSTANTS FOR NEW YB-169 BRACHYTHERAPY SEEDS

被引:25
作者
MACPHERSON, MS
BATTISTA, JJ
机构
[1] UNIV WESTERN ONTARIO, DEPT ONCOL, LONDON, ON N6A 5C1, CANADA
[2] UNIV WESTERN ONTARIO, DEPT MED BIOPHYS, LONDON, ON N6A 5C1, CANADA
[3] LONDON REG CANC CTR, ONTARIO CANC TREATMENT & RES FDN, LONDON, ON N6A 4L6, CANADA
关键词
YB-169; BRACHYTHERAPY; THERMOLUMINESCENT DOSIMETRY; MONTE CARLO;
D O I
10.1118/1.597597
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Relative dose distributions in the vicinities of two new prototypes of ytterbium-169 brachytherapy sources have been measured using lithium fluoride thermoluminescent dosimeters (TLD) placed in a solid water phantom. The type 6 seed consists of four Yb203 spheres contained in a 0.075-mm thick titanium tube, with overall dimensions of 4.5 mm in length and 0.8 mm in diameter. The type 8 seed contains a cylindrical segment of Yb wire, 2.5 mm long, sealed in a 0.075-mm thick titanium tube 4 mm in length and 0.5 mm in diameter. The relative dose distributions, measured with TLD, were compared with those predicted by Monte Carlo simulations (MCNP code). Experimental and theoretical dose distributions were generally in agreement within 5% of the local dose value. Source strength was determined from activity measurements using a high purity germanium (HPGe) spectrometer. With source strengths established, thermoluminescence was then used to measure the dose rate constant, A0, for the type 8 seed. The measured A0of 1.34±0.10 cGy U-1 for the type 8 seed agrees, within statistical uncertainty, with the value of 1.25±0.05 cGyU-1predicted through Monte Carlo simulation. Comparisons are made with experimental data reported by other investigators. © 1995, American Association of Physicists in Medicine. All rights reserved.
引用
收藏
页码:89 / 96
页数:8
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