DEACETOXYCEPHALOSPORIN-C SYNTHETASE AND DEACETOXYCEPHALOSPORIN-C HYDROXYLASE ARE 2 SEPARATE ENZYMES IN STREPTOMYCES-CLAVULIGERUS

被引：81

作者：

JENSEN, SE ^{[1
]}

WESTLAKE, DWS ^{[1
]}

WOLFE, S ^{[1
]}

机构：

[1] QUEENS UNIV,DEPT CHEM,KINGSTON K7L 3N6,ONTARIO,CANADA

来源：

JOURNAL OF ANTIBIOTICS | 1985年 / 38卷 / 02期

关键词：

D O I：

10.7164/antibiotics.38.263

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：263 / 265

页数：3

共 8 条

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[2]

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[3] STIMULATION OF THE CONVERSION OF PENICILLIN N TO CEPHALOSPORIN BY ASCORBIC-ACID ALPHA-KETOGLUTARATE, AND FERROUS-IONS IN CELL-FREE-EXTRACTS OF STRAINS OF CEPHALOSPORIUM-ACREMONIUM [J].

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[4] ANALYSIS OF PENICILLIN-N RING EXPANSION ACTIVITY FROM STREPTOMYCES-CLAVULIGERUS BY ION-PAIR HIGH-PRESSURE LIQUID-CHROMATOGRAPHY [J].

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[5] CEPHALOSPORIN FORMATION BY CELL-FREE-EXTRACTS FROM STREPTOMYCES-CLAVULIGERUS [J].

JENSEN, SE ;

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[6]

KUPKA J, 1983, FEMS MICROBIOL LETT, V16, P1

[7] PARTIAL-PURIFICATION AND CATALYTIC PROPERTIES OF A BIFUNCTIONAL ENZYME IN THE BIOSYNTHETIC-PATHWAY OF BETA-LACTAMS IN CEPHALOSPORIUM-ACREMONIUM [J].

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JOURNAL OF ANTIBIOTICS, 1984, 37 (05) :522-531

[8] OXYGENATION OF [3-METHYL-H-3]DESACETOXYCEPHALOSPORIN-C [7-BETA-D-AMINOADIPAMIDO)-3-METHYLCEPH-3-EM-4-CARBOXYLIC ACID] TO [3-HYDROXYMETHYL-H-3]DESACETYLCEPHALOSPORIN-C BY 2-OXOGLUTARATE-LINKED DIOXYGENASES FROM ACREMONIUM-CHRYSOGENUM AND STREPTOMYCES-CLAVULIGERUS [J].

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