ANALYSIS OF METHOTREXATE AND 7-HYDROXYMETHOTREXATE BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY AND PRELIMINARY CLINICAL-STUDIES

被引：22
作者：
COLLIER, CP
MACLEOD, SM
SOLDIN, SJ
机构：
[1] HOSP SICK CHILDREN, INST RES, DEPT BIOCHEM, TORONTO M5G 1X8, ONTARIO, CANADA
[2] UNIV TORONTO, DEPT CLIN BIOCHEM, TORONTO M5S 1A1, ONTARIO, CANADA
[3] UNIV TORONTO, DEPT PHARMACOL, TORONTO M5S 1A1, ONTARIO, CANADA
来源：
THERAPEUTIC DRUG MONITORING | 1982年 / 4卷 / 04期
关键词：
D O I：
10.1097/00007691-198212000-00007
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
引用
收藏
页码：371 / 380
页数：10
相关论文
共 26 条
[21]   USE OF PLASMA PHARMACOKINETICS TO PREDICT AND PREVENT METHOTREXATE TOXICITY [J].
STOLLER, RG ;
HANDE, KR ;
JACOBS, SA ;
ROSENBERG, SA ;
CHABNER, BA .
NEW ENGLAND JOURNAL OF MEDICINE, 1977, 297 (12) :630-634
[22]   A DIRECT ANALYSIS OF METHOTREXATE, DICHLORO-METHOTREXATE AND THEIR 7-HYDROXY METABOLITES IN PLASMA BY HIGH-PRESSURE LIQUID-CHROMATOGRAPHY [J].
TONG, WP ;
WISNICKI, JL ;
HORTON, J ;
LUDLUM, DB .
CLINICA CHIMICA ACTA, 1980, 107 (1-2) :67-72
[23]  
VONHOFF DD, 1977, CANCER TREAT REP, V61, P745
[24]   PAIRED-ION HIGH-PRESSURE LIQUID-CHROMATOGRAPHY OF METHOTREXATE AND METABOLITES IN BIOLOGICAL-FLUIDS [J].
WANG, YM ;
HOWELL, SK ;
BENVENUTO, JA .
JOURNAL OF LIQUID CHROMATOGRAPHY, 1980, 3 (07) :1071-1078
[25]  
WATSON E, 1978, CANCER TREAT REP, V62, P381
[26]  
WESTGARD JO, 1978, AM J MED TECHNOL, V44, P552
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