A HIV-infected adolescent with polycystic ovary syndrome

被引:1
作者
Dejkhamron, Prapai [1 ]
Unachak, Kevalee [1 ]
Chhabra, Manik [2 ]
Oberdorfer, Peninnah [3 ]
机构
[1] Chiang Mai Univ, Fac Med, Dept Pediat, Div Endocrinol, Chiang Mai, Thailand
[2] Univ Minnesota, Dept Med, Minneapolis, MN 55455 USA
[3] Chiang Mai Univ, Fac Med, Dept Pediat, Div Infect Dis, Chiang Mai 50200, Thailand
关键词
PCOS; HIV; HAART;
D O I
10.3233/JPI-2011-0284
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We report a case of polycystic ovary syndrome in a 15-year-old human immunodeficiency virus-infected female on highly active antiretroviral therapy who developed hypertriglyceridemia, hyperinsulinemia due to insulin resistance, and hyperandrogenism. Ultrasonography showed multiple small follicles at the right ovary and lobulated follicles at the left ovary. Treatment of polycystic ovary syndrome included insulin sensitizing agents (metformin, pioglitazone) and a contraceptive for hyperandrogenism. We also encouraged life style modification including regular exercise and dietary fat restriction. She attained menarche 1 month after initiation of treatment.
引用
收藏
页码:45 / 49
页数:5
相关论文
共 24 条
  • [1] Aurpibul L, 2007, ANTIVIR THER, V12, P1247
  • [2] Screening for 21-hydroxylase-deficient nonclassic adrenal hyperplasia among hyperandrogenic women: a prospective study
    Azziz, R
    Hincapie, LA
    Knochenhauer, ES
    Dewailly, D
    Fox, L
    Boots, LR
    [J]. FERTILITY AND STERILITY, 1999, 72 (05) : 915 - 925
  • [3] Polycystic ovary syndrome in adolescence
    Buggs, C
    Rosenfield, RL
    [J]. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 2005, 34 (03) : 677 - +
  • [4] A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors
    Carr, A
    Samaras, K
    Burton, S
    Law, M
    Freund, J
    Chisholm, DJ
    Cooper, DA
    [J]. AIDS, 1998, 12 (07) : F51 - F58
  • [5] Cherry Catherine L, 2005, Sex Health, V2, P1, DOI 10.1071/SH04016
  • [6] Lipodystrophy in pediatric HIV
    Desai, Ninad
    Mullen, Patricia
    Mathur, Mudit
    [J]. INDIAN JOURNAL OF PEDIATRICS, 2008, 75 (04) : 351 - 354
  • [7] Glucose metabolism, lipid, and body fat changes in antiretroviral-naive subjects randomized to nelfinavir or efavirenz plus dual nucleosides
    Dubé, MP
    Parker, RA
    Tebas, P
    Grinspoon, SK
    Zackin, RA
    Robbins, GK
    Roubenoff, R
    Shafer, RW
    Wininger, DA
    Meyer, WA
    Snyder, SW
    Mulligan, K
    [J]. AIDS, 2005, 19 (16) : 1807 - 1818
  • [8] HIV and mitochondrial toxicity in children
    Foster, Caroline
    Lyall, Hermione
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2008, 61 (01) : 8 - 12
  • [9] Fasting hyperinsulinemia and changes in regional body composition in human immunodeficiency virus-infected women
    Hadigan, C
    Miller, K
    Corcoran, C
    Anderson, E
    Basgoz, N
    Grinspoon, S
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (06) : 1932 - 1937
  • [10] Current approaches to the diagnosis and treatment of polycystic ovarian syndrome in youth
    Harwood, Katerina
    Vuguin, Patricia
    DiMartino-Nardi, Joan
    [J]. HORMONE RESEARCH, 2007, 68 (05) : 209 - 217