DIFFUSION-WEIGHTED IMAGING IN EPILEPSY

被引：33

作者：

HELPERN, JA

HUANG, N

机构：

[1] Division of Medical Physics, The Nathan Kline Institute, Orangeburg

[2] Department of Psychiatry, New York University Medical Center, New York

[3] Department of Radiology, New York University Medical Center, New York

来源：

MAGNETIC RESONANCE IMAGING | 1995年 / 13卷 / 08期

关键词：

DIFFUSION; MAGNETIC RESONANCE IMAGING; EPILEPSY; EDEMA; ISCHEMIA;

D O I：

10.1016/0730-725X(95)02036-S

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Diffusion-weighted imaging (DWI) is a relatively new magnetic resonance imaging (MRI) technique that can be used to probe the microenvironment of water. Contrast in DWI depends on properties different from traditional T-1 and T-2 contrast, and is derived from the translational motion of water molecules. Since it is reasonable to think that a change in the microenvironment of water might be reflected in a change in water diffusion characteristics, the quantitative assessment of the (apparent) diffusion coefficient ADCw may represent a unique means of assessing tissue status. DWI has already shown great utility in the study of cerebral ischemia in animal models and has proved useful in the early identification of cerebral ischemia in patients. More recent reports have indicated a potential for DWI in studying epilepsy. Here, we briefly review some of what is known about the measurement of ADCw in ischemia and compare these results with what has recently been reported for epilepsy. In this manner we hope to better understand the underlying mechanisms behind changes in water diffusion associated with specific pathologies.

引用

页码：1227 / 1231

页数：5

共 32 条

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