SYNTHESIS OF A BICYCLIC MODEL FOR THE MARINE HEPATOTOXIN CYLINDROSPERMOPSIN

被引：25

作者：

SNIDER, BB

HARVEY, TC

机构：

[1] Department of Chemistry Brandeis University, Waltham, MA 02254

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 26期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0040-4039(95)00872-A

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A double Michael addition of ammonia to dienone 9 to give piperidinone 10 and the reaction of diamine 16 with isothiocyanate 19 to give protected guanidine 18 are the key transformations in a ten-step synthesis of the cylindrospermopsin model 22.

引用

页码：4587 / 4590

页数：4

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