SYNTHESIS OF A BICYCLIC MODEL FOR THE MARINE HEPATOTOXIN CYLINDROSPERMOPSIN

被引：25
作者：
SNIDER, BB
HARVEY, TC
机构：
[1] Department of Chemistry Brandeis University, Waltham, MA 02254
来源：
TETRAHEDRON LETTERS | 1995年 / 36卷 / 26期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/0040-4039(95)00872-A
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A double Michael addition of ammonia to dienone 9 to give piperidinone 10 and the reaction of diamine 16 with isothiocyanate 19 to give protected guanidine 18 are the key transformations in a ten-step synthesis of the cylindrospermopsin model 22.
引用
收藏
页码：4587 / 4590
页数：4
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