SERUM GASTRIN VALUES IN PATIENTS WITH FAMILIAL ADENOMATOUS POLYPOSIS

被引：3
作者：
SVENDSEN, LB
BISGARD, ML
GUSTAFSEN, J
BULOW, S
STADIL, F
机构：
[1] HVIDOVRE UNIV HOSP,DEPT SURG GASTROENTEROL,COPENHAGEN,DENMARK
[2] UNIV COPENHAGEN,INST HUMAN GENET,COPENHAGEN,DENMARK
来源：
DISEASES OF THE COLON & RECTUM | 1994年 / 37卷 / 01期
关键词：
FAMILIAL ADENOMATOUS POLYPOSIS; GASTRIN; COLORECTAL CANCER;
D O I：
10.1007/BF02047209
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
PURPOSE: An evaluation of the importance of gastrin in the colorectal carcinogenesis in patients with familial adenomatous polyposis was conducted. METHODS: Blood samples from 168 family members of 26 families were investigated for circulating gastrin. Blood was drawn from 65 affected patients, 66 clinically unaffected first-degree relatives, and 37 spouses. RESULTS: We did not find any difference in distribution of serum gastrin among these groups. CONCLUSION: Our results seem to exclude gastrin from being relevant in early carcinogenesis in patients with familial adenomatous polyposis.
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页码：22 / 25
页数：4
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