Antiphospholipid syndrome leading to venous brain thrombosis in an elderly patient

Antiphospholipid syndrome (APS) is a systemic autoimmune condition characterized by hypercoagulability, venous and/or arterial thromboses, and miscarriages. APS can be diagnosed according to specific criteria and is usually observed in young adults. We report a case of an elderly woman with past history of thrombosis and miscarriages who developed severe brain parenchymal hemorrhage and extensive thrombosis of the superior sagittal sinus due to APS. This case emphasizes that, although rare, APS may be diagnosed in elderly individuals and require effective anticoagulation. Copyright (C) 2014, Asia Pacific League of Clinical Gerontology & Geriatrics. Published by Elsevier Taiwan LLC.