SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME BENZIMIDAZOLE DERIVATIVE WITH IBUPROFEN

被引:8
作者
Ibrahim, K. Seiyadu [1 ]
Begum, Jesima [2 ]
机构
[1] King Khalid Univ Hosp, Riyadh, Saudi Arabia
[2] Periyar Coll Pharm, Tiruchirappalli, India
关键词
Benzimidazole; Ibuprofen; Synthesis; Antibacterial; Antifungal;
D O I
10.13040/IJPSR.0975-8232.2(2).298-02
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Some novel benzimidazole derivatives were synthesized with ibuprofen and evaluated for its activity. This compound showed notable antibacterial activity against gram-positive organisms and antifungal activity against when compared with respective standards.
引用
收藏
页码:298 / 302
页数:5
相关论文
共 22 条
[1]  
[Anonymous], 1996, INDIAN PHARMACOPOEIA, V1, P250
[2]  
BENAVIDES J, 1995, ARZNEIMITTELFORSCH, V45-1, P551
[3]  
Berg K H, 1986, ZYWIETZ MYKOSEN, V29, P221
[4]  
CHEN AY, 1993, CANCER RES, V53, P1332
[5]  
CHIMIRRI A, 1991, FARMACO, V46, P925
[6]   SUBSTITUTED 2-(2-HYDROXYPHENYL)BENZIMIDAZOLES AS POTENTIAL AGENTS FOR THE CONTROL OF PERIODONTAL-DISEASES [J].
COBURN, RA ;
CLARK, MT ;
EVANS, RT ;
GENCO, RJ .
JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (01) :205-208
[7]   POTENTIAL ANTITUMOR AGENTS .59. STRUCTURE-ACTIVITY-RELATIONSHIPS FOR 2-PHENYLBENZIMIDAZOLE-4-CARBOXAMIDES, A NEW CLASS OF MINIMAL DNA-INTERCALATING AGENTS WHICH MAY NOT ACT VIA TOPOISOMERASE-II [J].
DENNY, WA ;
REWCASTLE, GW ;
BAGULEY, BC .
JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (02) :814-819
[8]   Synthesis of a group of 1H-benzimidazoles and their screening for antiinflammatory activity [J].
Evans, D ;
Hicks, TA ;
Williamson, WRN ;
Dawson, W ;
Meacock, SCR ;
Kitchen, EA .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1996, 31 (7-8) :635-642
[9]   Synthesis and antiviral assays of some 2-substituted benzimidazole-N-carbamates [J].
Garuti, L ;
Roberti, M ;
Gentilomi, G .
FARMACO, 2000, 55 (01) :35-39
[10]  
Goker K S, 1995, ARCH PHARM WEINHEIM, V328, P425