NOVEL GENETICALLY-ENGINEERED TETRACENOMYCINS

被引：40
|
作者：
DECKER, H
HAAG, S
UDVARNOKI, G
ROHR, J
机构：
[1] UNIV GOTTINGEN,INST ORGAN CHEM,D-37077 GOTTINGEN,GERMANY
[2] UNIV TUBINGEN,INST BIOL 2,D-72076 TUBINGEN,GERMANY
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1995年 / 34卷 / 10期
关键词：
BIOSYNTHESIS; GENE TECHNOLOGY; POLYKETIDES; TETRACENOMYCINS;
D O I：
10.1002/anie.199511071
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Genetically engineered hybrid strains, in which the genes of the urdamycin‐producer Streptomyce fradiae are combined with some of the biosynthetic genes of the elloramycin‐producer Streptomyces olivaceus or the genes of the tetracenomycin‐producer Streptomyces glaucescens, assemble novel hybrid antibiotics of the tetracenomycin type. The results prove that this combinatorial biosynthesis method may be a useful alternative for the production of new natural products which can then be screened. Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany
引用
收藏
页码：1107 / 1110
页数：4
相关论文
共 50 条
  • [21] Generation of genetically-engineered animals using engineered endonucleases
    Jong Geol Lee
    Young Hoon Sung
    In-Jeoung Baek
    Archives of Pharmacal Research, 2018, 41 : 885 - 897
  • [22] THE GENETICALLY-ENGINEERED RUBBER TREE - A NOVEL-APPROACH TO THE PRODUCTION OF PHARMACEUTICALS
    PANG, T
    AUSTRALASIAN BIOTECHNOLOGY, 1995, 5 (02) : 72 - 72
  • [23] Genetically-Engineered Meanderline Twist Reflector
    Han, Kyu Y.
    Lail, Brian A.
    2008 IEEE ANTENNAS AND PROPAGATION SOCIETY INTERNATIONAL SYMPOSIUM, VOLS 1-9, 2008, : 815 - 818
  • [24] MARIBO TRIALS WITH GENETICALLY-ENGINEERED BEET
    不详
    ZUCKERINDUSTRIE, 1993, 118 (08): : 643 - 643
  • [25] GRAFTING GENETICALLY-ENGINEERED CELLS TO THE BRAIN
    GAGE, FH
    FASEB JOURNAL, 1994, 8 (04): : A1 - A1
  • [26] Pharmacokinetics and biodistribution of genetically-engineered antibodies
    Colcher, D
    Pavlinkova, G
    Beresford, G
    Booth, BJM
    Choudhury, A
    Batra, SK
    QUARTERLY JOURNAL OF NUCLEAR MEDICINE, 1998, 42 (04): : 225 - 241
  • [27] GENETICALLY-ENGINEERED HUMAN PULMONARY SURFACTANT
    BENSON, BJ
    CLINICS IN PERINATOLOGY, 1993, 20 (04) : 791 - 811
  • [28] Comprehensive behavioral analysis of genetically-engineered mice
    Miyakawa, Tsuyoshi
    NEUROSCIENCE RESEARCH, 2006, 55 : S20 - S20
  • [29] METABOLISM OF POLYHALOGENATED COMPOUNDS BY A GENETICALLY-ENGINEERED BACTERIUM
    WACKETT, LP
    SADOWSKY, MJ
    NEWMAN, LM
    HUR, HG
    LI, SY
    NATURE, 1994, 368 (6472) : 627 - 629
  • [30] GENETICALLY-ENGINEERED SYNTHESIS OF NATURAL-PRODUCTS
    SCOTT, AI
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1993, 206 : 4 - ORGN
12345