TRANSFORMING GROWTH-FACTOR RECEPTOR GENE TGFBR2 MAPS TO HUMAN-CHROMOSOME BAND 3P22

被引：45

作者：

MATHEW, S

MURTY, VVVS

CHEIFETZ, S

GEORGE, D

MASSAGUE, J

CHAGANTI, RSK

机构：

[1] MEM SLOAN KETTERING CANC CTR,DEPT PATHOL,NEW YORK,NY 10021

[2] MEM SLOAN KETTERING CANC CTR,HOWARD HUGHES MED INST,NEW YORK,NY 10021

来源：

GENOMICS | 1994年 / 20卷 / 01期

关键词：

D O I：

10.1006/geno.1994.1134

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

In this study, we map the chromosomal position of the gene that encodes the type II receptor of TGF-beta (HGM symbol TGFBR2), a multifunctional regulator of cell proliferation and differentiation. Using a full-length cDNA and a genomic probe in Southern blot analysis of a human x rodent somatic cell hybrid panel and by direct fluorescence in situ hybridization to normal metaphase chromosomes, we show that the TGFBR2 gene maps to 3p22. (C) 1994 Academic Press, Inc.

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页码：114 / 115

页数：2

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