PHARMACOKINETICS OF SUBCUTANEOUS RECOMBINANT INTERLEUKIN-2 ADMINISTRATION IN CANCER-PATIENTS

被引:0
|
作者
CARUSO, B
GIAVARINA, D
JIRILLO, A
GIAVARINA, M
BALLI, M
机构
[1] LEGNAGO HOSP,CLIN CHEM LAB,VERONA,ITALY
[2] LEGNAGO HOSP,DEPT RADIOTHERAPY & ONCOL,VERONA,ITALY
来源
EOS-RIVISTA DI IMMUNOLOGIA ED IMMUNOFARMACOLOGIA | 1992年 / 12卷 / 04期
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Data from a clinical trial with recombinant Interleukin (rIL-2) subcutaneousy administered are here reported. Five patients with cancer were administered with r-IL2. Serum levels were measured on serial samples by immunoenzymatic method. This method is easier than biological methods, allowing to measure rIL-2 only as antigen. Therefore, immunoenzymatic method can be on support in the comprehensive study of IL-2 farmacokynetic. rIL-2 was detectable in serum in all the patient treated, with different levels and time.
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页码:207 / 209
页数:3
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