PREPARATION OF THE GEOMETRIC ISOMERS OF DDC, DDA, D4C AND D4T AS POTENTIAL ANTI-HIV AGENTS

被引：71

作者：

MANSURI, MM ^{[1
]}

FARINA, V ^{[1
]}

STARRETT, JE ^{[1
]}

BENIGNI, DA ^{[1
]}

BRANKOVAN, V ^{[1
]}

MARTIN, JC ^{[1
]}

机构：

[1] ONCOGEN,SEATTLE,WA 98121

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1991年 / 1卷 / 01期

关键词：

D O I：

10.1016/S0960-894X(01)81093-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Beta-L-ddC (5), beta-L-ddA (6), beta-L-d4T (7) and beta-L-d4C (8) (enantiomers of natural dideoxynucleoside analogues with known potent HIV activity) were prepared as potential anti-HIV agents.

引用

页码：65 / 68

页数：4

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