Geographic tongue treated with topical tacrolimus

被引：22

作者：

Ishibashi, Masaya ^{[1
]}

Tojo, Genichi ^{[2
]}

Watanabe, Masahiko ^{[3
]}

Tamabuchi, Takahiro ^{[4
]}

Masu, Takashi ^{[4
]}

Aiba, Setsuya ^{[2
]}

机构：

[1] Tohoku Univ Hosp, Dept Dermatol, Sendai, Miyagi, Japan

[2] Tohoku Univ, Grad Sch Med, Dept Dermatol, Sendai, Miyagi, Japan

[3] Sendai Teishin Hosp, Dept Dermatol, Sendai, Miyagi, Japan

[4] Ishinomaki Red Cross Hosp, Dept Dermatol, Ishinomaki, Miyagi, Japan

来源：

JOURNAL OF DERMATOLOGICAL CASE REPORTS | 2010年 / 4卷 / 04期

关键词：

benign migratory glossitis; calcineurin inhibitors; geographic tongue; tacrolimus; treatment;

D O I：

10.3315/jdcr.2010.1058

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background: Geographic tongue, or benign migratory glossitis, is usually an asymptomatic inflammatory disorder of the tongue mucosa of unknown etiology. It is characterized by circinate, erythematous, ulcer-like lesions of the dorsum and lateral border of the tongue due to loss of filiform papillae of the tongue epithelium. Symptomatic treatments have not been evaluated rigorously. Main observation: We describe herein two cases of adult patients with persistent and painful geographic tongue successfully treated with topical application of 0.1% tacrolimus ointment. Conclusion: To our knowledge, this is the first report of successful treatment with topical 0.1% tacrolimus for symptomatic geographic tongue. Clinical trials are needed to confirm the efficacy and the safety of topical tacrolimus in treating geographic tongue.

引用

页码：57 / 59

页数：3

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