CONTACT ALLERGY TO TIOCONAZOLE

被引：21
作者：
STUBB, S
HEIKKILA, H
REITAMO, S
FORSTROM, L
机构：
[1] Department of Dermatology, Helsinki University Central Hospital, Helsinki
来源：
CONTACT DERMATITIS | 1992年 / 26卷 / 03期
关键词：
IMIDAZOLE DERIVATIVES; TIOCONAZOLE; ALLERGIC CONTACT DERMATITIS; MEDICAMENTS; CROSS-SENSITIVITY;
D O I：
10.1111/j.1600-0536.1992.tb00285.x
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
In 15 months, we detected allergic patch test reactions to tioconazole in 14 patients. 9 of the 14 patients were allergic to additional imidazole derivatives used as antifungal agents. The positive patch test reactions to tioconazole may have been caused either by simultaneous sensitization or more probably by cross-reactivity between the various commercially used imidazole derivatives with a similar chemical structure. The abundant use of tioconazole in concentrated (up to 28%) topical formulations in Finland could be the major cause of the apparent increase in allergic reactions.
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收藏
页码：155 / 158
页数：4
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