GUANINE QUARTETS

被引：115

作者：

WILLIAMSON, JR

机构：

[1] Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, Bldg 56-331, Massachusetts Avenue

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1993年 / 3卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0959-440X(05)80106-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Guanine nucleotides form an extremely stable hydrogen-bonded structure composed of four bases, known as the guanine quartet. Guanine-rich sequences, in particular telomeric DNAs, can readily form these structures. New X-ray and NMR studies highlight the progress in understanding these structures. The role of monovalent ions in polymorphism and the unusual kinetic and thermodynamic stability of guanine-quartet structures is examined.

引用

页码：357 / 362

页数：6

共 36 条

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