TOTAL SYNTHESIS AND EVALUATION OF (+/-)-N-(TERT-BUTYLOXYCARBONYL)-CBI, (+/-)-CBI-CDPI1, AND (+/-)-CBI-CDPI2 - CC-1065 FUNCTIONAL AGENTS INCORPORATING THE EQUIVALENT 1,2,9,9A-TETRAHYDROCYCLOPROP[1,2-C]BENZ[1,2-E]INDOL-4-ONE (CBI) LEFT-HAND SUBUNIT

被引：207

作者：

BOGER, DL ^{[1
]}

ISHIZAKI, T ^{[1
]}

WYSOCKI, RJ ^{[1
]}

MUNK, SA ^{[1
]}

KITOS, PA ^{[1
]}

SUNTORNWAT, O ^{[1
]}

机构：

[1] UNIV KANSAS,DEPT BIOCHEM,LAWRENCE,KS 66045

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1989年 / 111卷 / 16期

关键词：

D O I：

10.1021/ja00198a089

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：6461 / 6463

页数：3

共 22 条

[1] STUDIES ON THE TOTAL SYNTHESIS OF CC-1065 - PREPARATION OF A SYNTHETIC, SIMPLIFIED 3-CARBAMOYL-1,2-DIHYDRO-3H-PYRROLO[3,2-E]INDOLE DIMER/TRIMER/TETRAMER (CDPI DIMER/TRIMER/TETRAMER) AND DEVELOPMENT OF METHODOLOGY FOR PDE-I DIMER METHYL-ESTER FORMATION [J].

BOGER, DL ;

COLEMAN, RS ;

INVERGO, BJ .

JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (08) :1521-1530

[2] STREPTONIGRIN AND LAVENDAMYCIN PARTIAL STRUCTURES - PROBES FOR THE MINIMUM, POTENT PHARMACOPHORE OF STREPTONIGRIN, LAVENDAMYCIN, AND SYNTHETIC QUINOLINE-5,8-DIONES [J].

BOGER, DL ;

YASUDA, M ;

MITSCHER, LA ;

DRAKE, SD ;

KITOS, PA ;

THOMPSON, SC .

JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (10) :1918-1928

[3] TOTAL SYNTHESIS OF (+/-)-N-(PHENYLSULFONYL)-CI AND (+/-)-N-(TERT-BUTYLOXYCARBONYL)-CI, (+/-)-CI-CDPI1, AND (+/-)-CI-CDPI2 - CC-1065 FUNCTIONAL ANALOGS INCORPORATING THE PARENT 1,2,7,7A-TETRAHYDROCYCLOPROP[1,2-C]INDOL-4-ONE (CI) LEFT-HAND SUBUNIT [J].

BOGER, DL ;

WYSOCKI, RJ .

JOURNAL OF ORGANIC CHEMISTRY, 1989, 54 (06) :1238-1240

[4] TOTAL SYNTHESIS OF (+/-)-N-2-(PHENYLSULFONYL)-CPI, (+/-)-CC-1065, (+)-CC-1065, ENT-(-)-CC-1065, AND THE PRECISE, FUNCTIONAL AGENTS (+/-)-CPI-CDPI2, (+)-CPI-CDPI2, AND (-)-CPI-CDPI2 [(+/-)-(3BR-STAR,4AS-STAR)-DEOXY-CC-1065, (+)-(3BR,4AS)-DEOXY-CC-1065, AND (-)-(3BS,4AR)-DEOXY-CC-1065] [J].

BOGER, DL ;

COLEMAN, RS .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (14) :4796-4807

[5]

BOGER DL, UNPUB

[6]

BOGER DL, 1989, STUDIES NATURAL PROD, V3

[7]

BOGER DL, IN PRESS CHEM BIOL I

[8] A BIFURCATED HYDROGEN-BONDED CONFORMATION IN THE D(A.T) BASE-PAIRS OF THE DNA DODECAMER D(CGCAAATTTGCG) AND ITS COMPLEX WITH DISTAMYCIN [J].

COLL, M ;

FREDERICK, CA ;

WANG, AHJ ;

RICH, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (23) :8385-8389

[9] MOLECULAR-STRUCTURE OF THE NETROPSIN-D(CGCGATATCGCG) COMPLEX - DNA CONFORMATION IN AN ALTERNATING AT SEGMENT [J].

COLL, M ;

AYMAMI, J ;

VANDERMAREL, GA ;

VANBOOM, JH ;

RICH, A ;

WANG, AHJ .

BIOCHEMISTRY, 1989, 28 (01) :310-320

[10] THE DESIGN AND APPLICATION OF FREE-RADICAL CHAIN REACTIONS IN ORGANIC-SYNTHESIS .1. [J].

CURRAN, DP .

SYNTHESIS-STUTTGART, 1988, (06) :417-439

← 1 2 3 →