Laparoscopic retroperitoneal lymph node dissection for testicular cancer

被引:9
作者
Hillelsohn, Joel H. [1 ]
Duty, Brian D. [1 ]
Okhunov, Zhamshid [1 ]
Kavoussi, Louis R. [1 ]
机构
[1] Arthur Smith Inst Urol, Lake Success, NY USA
关键词
Testicular cancer; Lymph node dissection; Laparoscopy; Retroperitoneal; Germ cell tumour;
D O I
10.1016/j.aju.2012.01.001
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Objectives: Laparoscopic retroperitoneal lymph node dissection (LRPLND) was introduced over 20 years ago as a less invasive alternative to open node dissection. In this review we summarise the indications, surgical technique and outcomes of L-RPLND in the treatment of testicular cancer. Methods: We searched MEDLINE using the terms 'laparoscopy', 'laparoscopic', retroperitoneal lymph node dissection', 'RPLND' and 'testicular neoplasms'. Articles were selected on the basis of their relevance, study design and content, with an emphasis on more recent data. Results: We found 14 pertinent studies, which included > 1300 patients who received either L-RPLND (515) or open RPLND (788). L-RPLND was associated with longer mean operative times (204 vs. 186 min), but shorter hospital stays (3.3 vs. 6.6 days) and lower complication rates (15.6% vs. 33%). Oncological outcomes were similar between L-RPLND and open RPLND, with local relapse rates of 1.3% and 1.4%, incidence of distal progression of 3.3% and 6.1%, biochemical failure in 0.9% and 1.1% and cure rates of 100% and 99.6%, respectively. Conclusion: There are no randomised controlled studies comparing L-RPLND with open RPLND. A review of case and comparative series showed similar perioperative and oncological outcomes. Patients undergoing L-RPLND on average have shorter hospital stays, a quicker return to normal activity and improved cosmesis. (C) 2012 Arab Association of Urology. Production and hosting by Elsevier B.V. All rights reserved.
引用
收藏
页码:66 / 73
页数:8
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