WHAT ARE THE MECHANISMS OF PHOTORECEPTOR ADAPTATION

被引：39
作者：
BOWNDS, MD
ARSHAVSKY, VY
机构：
[1] HARVARD UNIV,SCH MED,BOSTON,MA 02114
[2] MASSACHUSETTS EYE & EAR INFIRM,BOSTON,MA 02114
来源：
BEHAVIORAL AND BRAIN SCIENCES | 1995年 / 18卷 / 03期
关键词：
CALCIUM; CYCLIC GMP; CYCLIC GMP PHOSPHODIESTERASE; GUANYLATE CYCLASE; LIGHT ADAPTATION; PHOSPHORYLATION; PHOTORECEPTOR; RHODOPSIN; ROD OUTER SEGMENTS; TRANSDUCIN;
D O I：
10.1017/S0140525X00039170
中图分类号：
B84 [心理学];
学科分类号：
04 ; 0402 ;
摘要：
This article evaluates each of the reactions known to be involved in visual transduction as a potential site for the regulation of light adaptation. Extensive evidence suggests that calcium acts as a feedback messenger at several different points and recent work suggests a role for cGMP in regulating the primary excitatory pathway. A conclusion is that adaptation is likely to be regulated by multiple and redundant mechanisms. The goal of future experimentation will be to determine the relative importance of each of these.
引用
收藏
页码：415 / 424
页数：10
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